| Entry |
|
|---|
| Name |
Clotrimazole (JP16/USP/INN);
Lotrimin (TN);
Mycelex (TN)
|
|---|
| Product |
|
|---|
| Generic |
CLOTRIMAZOLE (E. FOUGERA &), CLOTRIMAZOLE (Glenmark Generics), CLOTRIMAZOLE (Paddock Laboratories), CLOTRIMAZOLE (Physicians Total Care), CLOTRIMAZOLE (REMEDYREPACK), CLOTRIMAZOLE (Roxane Laboratories), CLOTRIMAZOLE (STAT RX USA LLC), CLOTRIMAZOLE (Taro Pharmaceuticals U.S.A.), CLOTRIMAZOLE (Taro Pharmaceuticals U.S.A.), CLOTRIMAZOLE (Teva Pharmaceuticals USA), CLOTRIMAZOLE TROCHE (Cardinal Health) |
|---|
| Formula |
C22H17ClN2
|
|---|
| Exact mass |
344.108
|
|---|
| Mol weight |
344.8368
|
|---|
| Structure |
     |
|---|
| Activity |
|
|---|
| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Target |
sterol 14alpha-demethylase ihibitor [KO: K05917] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
25 Urogenital and anal organ agents
252 Genital organ agents
2529 Others
D00282 Clotrimazole (JP16/USP/INN)
26 Epidermides
265 Antiparasitic dermatosis agents
2655 Imidazoles
D00282 Clotrimazole (JP16/USP/INN)
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
629 Miscellaneous
6290 Miscellaneous
D00282 Clotrimazole (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB18 Clotrimazole
D00282 Clotrimazole (JP16/USP/INN)
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and triazole derivatives
D01AC01 Clotrimazole
D00282 Clotrimazole (JP16/USP/INN)
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AF Imidazole derivatives
G01AF02 Clotrimazole
D00282 Clotrimazole (JP16/USP/INN)
USP drug classification [BR:br08302]
Antifungals
Antifungals, Systemic
Azole Antifungals
Clotrimazole
D00282 Clotrimazole (JP16/USP/INN)
Antiinfectives [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
sterol 14alpha-demethylase inhibitor [KO:K05917]
Imidazoles
Clotrimazole [ATC:A01AB18 D01AC01 G01AF02]
D00282 Clotrimazole (JP16/USP/INN)
 |
|---|
| Other DBs |
CAS: 23593-75-1 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 25
1 C8x C 11.7600 -18.0600
2 C8x C 11.7600 -19.4600
3 C8x C 12.9724 -20.1600
4 C8x C 14.1849 -19.4600
5 C8x C 14.1849 -18.0600
6 C8y C 12.9724 -17.3600
7 C1d C 12.9724 -15.9600
8 C8y C 12.9724 -14.5600
9 C8y C 11.3400 -15.9600
10 N4y N 14.5600 -15.9600
11 C8y C 10.6400 -14.7476
12 C8x C 9.2400 -14.7476
13 C8x C 8.5400 -15.9600
14 C8x C 9.2400 -17.1724
15 C8x C 10.6400 -17.1724
16 C8x C 14.1679 -13.8696
17 C8x C 14.1678 -12.4696
18 C8x C 12.9553 -11.7697
19 C8x C 11.7598 -12.4601
20 C8x C 11.7599 -13.8601
21 C8x C 15.3829 -17.0926
22 N5x N 16.7144 -16.6600
23 C8x C 16.7144 -15.2600
24 C8x C 15.3829 -14.8274
25 X Cl 10.6400 -13.3476
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 6 7 1
8 7 8 1
9 7 9 1
10 7 10 1
11 9 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 9 15 1
17 8 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 8 20 1
23 10 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 10 24 1
28 11 25 1
|
|---|
