| Entry |
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| Name |
Doxycycline (USP);
Doxycycline hydrate;
DOXY;
Monodox (TN);
Oracea (TN)
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| Product |
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| Generic |
DOXYCYCLINE (Eon Labs), DOXYCYCLINE MONOHYDRATE (Global Pharmaceuticals), DOXYCYCLINE (Heritage Pharmaceuticals), DOXYCYCLINE (KAISER FOUNDATION HOSPITALS), DOXYCYCLINE (Lannett Company), DOXYCYCLINE (Mylan Pharmaceuticals), DOXYCYCLINE (Mylan Pharmaceuticals), DOXYCYCLINE (Par Pharmaceutical), DOXYCYCLINE (Par Pharmaceutical), ORACEA (Physicians Total Care), DOXYCYCLINE MONOHYDRATE (Physicians Total Care), DOXYCYCLINE (Ranbaxy Pharmaceuticals), DOXYCYCLINE (Ranbaxy Pharmaceuticals), DOXYCYCLINE MONOHYDRATE (Watson Laboratories) |
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| Formula |
C22H24N2O8. H2O
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| Exact mass |
462.1638
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| Mol weight |
462.4498
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| Structure |
     |
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| Activity |
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| Remark |
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| Comment |
Semisynthetic tetracycline
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| Target |
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO: K01977] |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB22 Doxycycline
D00307 Doxycycline (USP)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01A TETRACYCLINES
J01AA Tetracyclines
J01AA02 Doxycycline
D00307 Doxycycline (USP)
USP drug classification [BR:br08302]
Antibacterials
Tetracyclines
Doxycycline
D00307 Doxycycline (USP)
Dental and Oral Agents
Doxycycline
D00307 Doxycycline (USP)
Dermatological Agents
Dermatological Anti-inflammatory Agents
Doxycycline
D00307 Doxycycline (USP)
Antiinfectives [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
16S rRNA of 30S ribosomal subunit inhibitor [KO:K01977]
Tetracyclines
Doxycycline [ATC:A01AB22 J01AA02]
D00307 Doxycycline (USP)
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| Other DBs |
CAS: 17086-28-1 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 33
1 C1y C 21.1216 -16.6614
2 C1z C 21.1506 -18.0502
3 C1y C 22.3391 -15.9818
4 C1y C 19.9277 -15.9523
5 C2y C 19.8983 -18.7358
6 C5x C 22.2978 -18.7653
7 C2y C 23.5269 -16.6969
8 C1y C 18.7103 -16.6379
9 C2y C 18.6985 -18.0324
10 O1a O 19.8924 -20.1364
11 C2y C 23.5151 -18.0857
12 O5x O 22.3208 -20.1660
13 O1a O 24.7564 -16.0173
14 C1y C 17.5048 -15.9345
15 C5x C 17.4929 -18.7298
16 C5a C 24.7149 -18.8068
17 C8y C 16.2990 -16.6261
18 C8y C 16.2931 -18.0265
19 O5x O 17.4929 -20.1245
20 N1a N 25.9383 -18.1212
21 O5a O 24.7439 -20.2073
22 C8x C 15.0755 -15.9286
23 C8y C 15.0815 -18.7240
24 C8x C 13.8699 -16.6319
25 C8x C 13.8699 -18.0324
26 O1a O 15.0815 -20.1245
27 C1a C 17.5101 -14.1705
28 N1c N 22.3622 -13.7280
29 C1a C 23.5981 -13.0412
30 C1a C 21.1494 -13.0011
31 O1a O 19.9173 -14.1846
32 O1a O 21.0956 -19.4620
33 O0 O 29.6802 -17.2901
BOND 35
1 5 9 2
2 5 10 1
3 6 11 1
4 6 12 2
5 7 13 1
6 8 14 1
7 9 15 1
8 11 16 1
9 14 17 1
10 15 18 1
11 15 19 2
12 16 20 1
13 16 21 2
14 17 22 1
15 18 23 1
16 22 24 2
17 23 25 2
18 23 26 1
19 7 11 2
20 8 9 1
21 17 18 2
22 24 25 1
23 14 27 1 #Down
24 3 28 1 #Down
25 1 2 1
26 28 29 1
27 1 3 1
28 28 30 1
29 1 4 1
30 2 5 1
31 2 6 1
32 4 31 1 #Down
33 3 7 1
34 2 32 1 #Down
35 4 8 1
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