KEGG   DRUG: D00308Help
Entry
D00308                      Drug                                   

Name
Droperidol (JP16/USP/INN);
Droleptan (TN);
Inapsine (TN)
Product
  Generic
Formula
C22H22FN3O2
Exact mass
379.1696
Mol weight
379.4274
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Butyrophenone derivatives
Target
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Butyrophenones
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AD Butyrophenone derivatives
     N05AD08 Droperidol
      D00308  Droperidol (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   111  General anesthetics
    1119  Others
     D00308  Droperidol (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Droperidol
      D00308  Droperidol (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00308  Droperidol
BRITE hierarchy
Other DBs
CAS: 
548-73-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   N4y N    34.7898  -14.1599
            2   C8y C    36.1337  -14.5455
            3   C2y C    33.5782  -14.8648
            4   C8y C    34.7636  -12.7484
            5   C8y C    36.9382  -13.4028
            6   C8x C    36.7369  -15.8127
            7   C1x C    33.5782  -16.2626
            8   C2x C    32.3726  -14.1599
            9   N4x N    36.0849  -12.2909
            10  O5x O    33.6158  -11.9504
            11  C8x C    38.3329  -13.5172
            12  C8x C    38.1331  -15.9387
            13  C1x C    32.3726  -16.9615
            14  C1x C    31.1553  -14.8648
            15  C8x C    38.9302  -14.7851
            16  N1y N    31.1612  -16.2626
            17  C1b C    29.9498  -16.9615
            18  C1b C    28.7325  -16.2626
            19  C1b C    27.5210  -16.9615
            20  C5a C    26.3037  -16.2626
            21  C8y C    25.0923  -16.9615
            22  O5a O    26.3037  -14.8648
            23  C8x C    23.8807  -16.2626
            24  C8x C    25.0923  -18.3593
            25  C8x C    22.6693  -16.9615
            26  C8x C    23.8866  -19.0642
            27  C8y C    22.6752  -18.3652
            28  X   F    21.4636  -19.0699
BOND        31
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     4  10 2
            10    5  11 1
            11    6  12 2
            12    7  13 1
            13    8  14 1
            14   11  15 2
            15   13  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   20  22 2
            22   21  23 2
            23   21  24 1
            24   23  25 1
            25   24  26 2
            26   25  27 2
            27   27  28 1
            28    5   9 1
            29   12  15 1
            30   14  16 1
            31   26  27 1

» Japanese version   » Back

DBGET integrated database retrieval system