| Entry |
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| Name |
Felodipine (JAN/USP/INN);
Plendil (TN)
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| Product |
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| Generic |
FELODIPINE (Aurobindo Pharma Limited), FELODIPINE (Bryant Ranch Prepack), FELODIPINE (Glenmark Generics), FELODIPINE (Mutual Pharmaceutical Company), FELODIPINE (Mylan Pharmaceuticals), FELODIPINE (NCS HealthCare of KY), FELODIPINE (PD-Rx Pharmaceuticals), FELODIPINE (PD-Rx Pharmaceuticals), FELODIPINE (Physicians Total Care), FELODIPINE (Qualitest Pharmaceuticals), FELODIPINE (REMEDYREPACK), FELODIPINE (Richmond Pharmaceuticals), FELODIPINE (Torrent Pharmaceuticals Limited), FELODIPINE (UDL Laboratories), FELODIPINE (WOCKHARDT LIMITED), FELODIPINE (WOCKHARDT USA LLC) |
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| Formula |
C18H19Cl2NO4
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| Exact mass |
383.0691
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| Mol weight |
384.2538
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| Structure |
     |
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| Activity |
Vasodilator
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| Remark |
Therapeutic category: ATC code: |
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| Target |
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| Pathway |
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
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| Interaction |
Transporter inhibition: ABCB1 [HSA: 5243]
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| Structure map |
| Calcium channel blocking drugs |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D00319 Felodipine (JAN/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C08 CALCIUM CHANNEL BLOCKERS
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
C08CA Dihydropyridine derivatives
C08CA02 Felodipine
D00319 Felodipine (JAN/USP/INN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Calcium Channel Blocking Agents
Dihydropyridines
Felodipine
D00319 Felodipine (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated cation channels
Ca2+ channel, CACN alpha-1, CaVx.x
calcium channel L type [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
Felodipine [ATC:C08CA02]
D00319 Felodipine (JAN/USP/INN)
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| Other DBs |
CAS: 72509-76-3 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 25
1 C1y C 23.3929 -16.6407
2 C8y C 23.3752 -18.9159
3 C2y C 22.2113 -15.9623
4 C2y C 24.5742 -15.9682
5 C8y C 22.1879 -19.5944
6 C8x C 24.5567 -19.6061
7 C2y C 22.2173 -14.5937
8 C7a C 21.0240 -16.6350
9 C2y C 24.5801 -14.6054
10 C7a C 25.7498 -16.6524
11 C8y C 22.1879 -20.9630
12 X Cl 21.0066 -18.9101
13 C8x C 24.5508 -20.9630
14 N1x N 23.3986 -13.9152
15 C1a C 21.0357 -13.9095
16 O7a O 19.8485 -15.9565
17 O6a O 21.0240 -18.0093
18 C1a C 25.7615 -13.9212
19 O7a O 26.9371 -15.9799
20 O6a O 25.7440 -18.0210
21 C8x C 23.3635 -21.6473
22 X Cl 21.0006 -21.6473
23 C1b C 18.6671 -16.6350
24 C1a C 28.1186 -16.6641
25 C1a C 17.4856 -15.9506
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 2
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 2
13 7 14 1
14 7 15 1
15 8 16 1
16 8 17 2
17 9 18 1
18 10 19 1
19 10 20 2
20 11 21 2
21 11 22 1
22 16 23 1
23 19 24 1
24 23 25 1
25 9 14 1
26 13 21 1
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