KEGG   DRUG: FlucytosineHelp
Entry
D00323                      Drug                                   

Name
Flucytosine (JP17/USP/INN);
5-FC;
Ancobon (TN)
Product
  Generic
Formula
C4H4FN3O
Exact mass
129.0338
Mol weight
129.0925
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Activity
Antifungal
Comment
Flucytosine is converted into Fluorouracil [DR:D00584] by susceptible fungal cells.
Target
DNA synthesis inhibitor;
RNA synthesis inhibitor
Interaction
Drug interaction
Structure map
Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE21 Flucytosine
      D00323  Flucytosine (JP17/USP/INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J02 ANTIMYCOTICS FOR SYSTEMIC USE
   J02A ANTIMYCOTICS FOR SYSTEMIC USE
    J02AX Other antimycotics for systemic use
     J02AX01 Flucytosine
      D00323  Flucytosine (JP17/USP/INN)
USP drug classification [BR:br08302]
 Antifungals
  Flucytosine
   D00323  Flucytosine (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   629  Miscellaneous
    6290  Miscellaneous
     D00323  Flucytosine (JP17/USP/INN)
Antiinfectives [BR:br08307]
 Antifungals
  Nucleic acid synthesis inhibitor
   Fluoropyrimidines
    Flucytosine
     D00323  Flucytosine (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00323  Flucytosine
Antifungals [br08352.html]
 D00323
BRITE hierarchy
Other DBs
CAS: 
2022-85-7
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        9
            1   C8y C    22.2270  -17.0929
            2   C8y C    23.4436  -16.4001
            3   N5x N    22.2270  -18.4957
            4   N1a N    21.0104  -16.3943
            5   C8x C    24.6486  -17.0929
            6   X   F    23.4436  -14.9972
            7   C8y C    23.4436  -19.1943
            8   N4x N    24.6486  -18.4957
            9   O5x O    23.4436  -20.5971
BOND        9
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     5   8 1
            8     7   9 2
            9     7   8 1

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