| Entry |
|
|---|
| Name |
Hydroxycarbamide (JAN/INN);
Hydroxyurea (USP);
Droxia (TN);
Hydrea (TN)
|
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
CH4N2O2
|
|---|
| Exact mass |
76.0273
|
|---|
| Mol weight |
76.0547
|
|---|
| Structure |
     |
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| Activity |
|
|---|
| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Target |
ribonucleotide reductase M2 inhibitor [HSA: 6241] [KO: K10808] |
|---|
| Pathway |
|
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| Interaction |
|
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| Structure map |
| Antineoplastics - antimetabolic agents |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
422 Antimetabolites
4229 Others
D00341 Hydroxycarbamide (JAN/INN); Hydroxyurea (USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX05 Hydroxycarbamide
D00341 Hydroxycarbamide (JAN/INN); Hydroxyurea (USP)
USP drug classification [BR:br08302]
Antineoplastics
Antimetabolites
Antimetabolites, Other
Hydroxyurea
D00341 Hydroxycarbamide (JAN/INN); Hydroxyurea (USP)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
ribonucleotide reductase M2 [HSA:6241] [KO:K10808]
Hydroxycarbamide [ATC:L01XX05]
D00341 Hydroxycarbamide (JAN/INN); Hydroxyurea (USP)
Antineoplastics [BR:br08308]
Miscellaneous agents
Substitued urea
Hydroxycarbamide [ATC:L01XX05]
D00341 Hydroxycarbamide (JAN/INN); Hydroxyurea (USP)
 |
|---|
| Other DBs |
CAS: 127-07-1 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 5
1 C5a C 25.2773 -18.3400
2 N1b N 26.4812 -19.0436
3 N1a N 24.0675 -19.0436
4 O5a O 25.2773 -16.9385
5 O1b O 27.6967 -18.3400
BOND 4
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
|
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