KEGG   DRUG: D00345Help
Entry
D00345                      Drug                                   

Name
Indapamide (JP16/USP);
Lozol (TN);
Natrix (TN)
Product
  Generic
Formula
C16H16ClN3O3S
Exact mass
365.0601
Mol weight
365.8345
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensice;
Diuretic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Sulfonamide derivatives - overview
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
    C03BA Sulfonamides, plain
     C03BA11 Indapamide
      D00345  Indapamide (JP16/USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Thiazide
   Indapamide
    D00345  Indapamide (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D00345  Indapamide (JP16/USP)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3
     Indapamide
      D00345  Indapamide (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00345  Indapamide
  D00345  Indapamide tablets
BRITE hierarchy
Other DBs
CAS: 
26807-65-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8x C    16.4080  -16.4924
            2   C8x C    16.4080  -17.8843
            3   C8x C    17.6134  -18.5803
            4   C8x C    18.8190  -17.8843
            5   C8y C    18.8190  -16.4924
            6   C8y C    17.6134  -15.7964
            7   N1y N    20.0245  -15.7964
            8   C1y C    19.5262  -14.4348
            9   C1x C    18.0723  -14.4284
            10  N1b N    21.2300  -16.4924
            11  C5a C    22.4355  -15.7964
            12  C1a C    20.3390  -13.2774
            13  C8y C    23.6841  -16.5171
            14  O5a O    22.4361  -14.4204
            15  C8x C    23.6842  -17.9198
            16  C8x C    24.8967  -18.6197
            17  C8y C    26.1091  -17.9196
            18  C8y C    26.1090  -16.5169
            19  C8x C    24.8965  -15.8170
            20  S4a S    27.3208  -15.8172
            21  X   Cl   27.3224  -18.6200
            22  N1a N    28.5332  -15.1172
            23  O3c O    26.6169  -14.5979
            24  O3c O    28.0167  -17.0226
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9   6 1
            11   10  11 1
            12    7  10 1
            13    8  12 1
            14   11  13 1
            15   11  14 2
            16   13  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   13  19 1
            22   18  20 1
            23   17  21 1
            24   20  22 1
            25   20  23 2
            26   20  24 2

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