KEGG   DRUG: D00353Help
Entry
D00353                      Drug                                   

Name
Lamivudine (JAN/USP/INN);
Epivir (TN)
Product
  Generic
Formula
C8H11N3O3S
Exact mass
229.0521
Mol weight
229.2562
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00406 H00412]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
Target
RNA-directed DNA polymerase inhibitor
Metabolism
Transporter: SLC22A6 [HSA:9356]
Interaction
Drug interaction
Structure map
Antiviral agents
Anti-HIV agents
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF05 Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Lamivudine
    D00353  Lamivudine (JAN/USP/INN)
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Lamivudine
    D00353  Lamivudine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00353  Lamivudine (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HBV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
  Anti-HIV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
134678-17-4
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   C1y C    43.8083  -23.2205
            2   N4y N    45.2094  -22.5476
            3   O2x O    42.6802  -22.4298
            4   C1x C    43.3964  -24.5390
            5   C8y C    46.3796  -21.8264
            6   C8x C    43.9940  -21.8893
            7   C1y C    41.5784  -23.2567
            8   S2x S    42.0214  -24.5614
            9   N5x N    46.3768  -20.3875
            10  O5x O    47.5912  -22.4780
            11  C8x C    43.9651  -20.5136
            12  C1b C    40.3778  -22.6348
            13  C8y C    45.1335  -19.7975
            14  O1a O    39.0672  -23.4248
            15  N1a N    45.0935  -18.4183
BOND        16
            1     1   2 1 #Down
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1 #Down
            12    9  13 2
            13   12  14 1
            14   13  15 1
            15    7   8 1
            16   11  13 1

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