KEGG   DRUG: LamivudineHelp
Entry
D00353                      Drug                                   

Name
Lamivudine (JAN/USP/INN);
Epivir (TN)
Product
  Generic
LAMIVUDINE (American Health Packaging), LAMIVUDINE (Apotex Corp.), LAMIVUDINE (Apotex Corp.), LAMIVUDINE (Aurobindo Pharma Limited), LAMIVUDINE (AvPAK), LAMIVUDINE (Bryant Ranch Prepack), LAMIVUDINE (Camber Pharmaceuticals), LAMIVUDINE (Camber Pharmaceuticals), LAMIVUDINE (Golden State Medical Supply), LAMIVUDINE (KAISER FOUNDATION HOSPITALS), LAMIVUDINE (KAISER FOUNDATION HOSPITALS), LAMIVUDINE (Lupin Pharmaceuticals), LAMIVUDINE (Marlex Pharmaceuticals), LAMIVUDINE (Mylan Pharmaceuticals), LAMIVUDINE (Mylan Pharmaceuticals), LAMIVUDINE (Prasco Laboratories), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (REMEDYREPACK), LAMIVUDINE (Silarx Pharmaceuticals), LAMIVUDINE (State of Florida DOH Central Pharmacy)
Formula
C8H11N3O3S
Exact mass
229.0521
Mol weight
229.2562
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor
 DG01656  HIV reverse transcriptase inhibitor
Remark
Same as: 
Therapeutic category: 
ATC code: 
Activity
Antiviral, Reverse transcriptase inhibitor
  Disease
HIV infection [DS:H01563]
Hepatitis B [DS:H00412]
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
Zidovudine type
Target
RNA-directed DNA polymerase
Metabolism
Transporter: SLC22A6 [HSA:9356]
Interaction
Drug interaction
Structure map
Antiviral agents
Anti-HIV agents
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF05 Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Lamivudine
    D00353  Lamivudine (JAN/USP/INN)
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Lamivudine
    D00353  Lamivudine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00353  Lamivudine (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HBV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitor (NRTIs)
     Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
  Anti-HIV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitor (NRTIs)
     Lamivudine
      D00353  Lamivudine (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 Transporter substrates
  OAT1
   Lamivudine
    D00353  Lamivudine (JAN/USP/INN)
Antivirals [br08351.html]
 D00353
BRITE hierarchy
Other DBs
CAS: 
134678-17-4
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   C1y C    43.8083  -23.2205
            2   N4y N    45.2094  -22.5476
            3   O2x O    42.6802  -22.4298
            4   C1x C    43.3964  -24.5390
            5   C8y C    46.3796  -21.8264
            6   C8x C    43.9940  -21.8893
            7   C1y C    41.5784  -23.2567
            8   S2x S    42.0214  -24.5614
            9   N5x N    46.3768  -20.3875
            10  O5x O    47.5912  -22.4780
            11  C8x C    43.9651  -20.5136
            12  C1b C    40.3778  -22.6348
            13  C8y C    45.1335  -19.7975
            14  O1a O    39.0672  -23.4248
            15  N1a N    45.0935  -18.4183
BOND        16
            1     1   2 1 #Down
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1 #Down
            12    9  13 2
            13   12  14 1
            14   13  15 1
            15    7   8 1
            16   11  13 1

» Japanese version   » Back

DBGET integrated database retrieval system