| Entry |
|
| Name |
Lamivudine (JAN/USP/INN);
Epivir (TN)
|
| Product |
EPIVIR (Bryant Ranch Prepack), EPIVIR (GlaxoSmithKline LLC), EPIVIR (GlaxoSmithKline LLC), EPIVIR (KAISER FOUNDATION HOSPITALS), EPIVIR (Physicians Total Care), EPIVIR (REMEDYREPACK), EPIVIR (REMEDYREPACK), EPIVIR (REMEDYREPACK), EPIVIR (REMEDYREPACK), EPIVIR (Rebel Distributors Corp), EPIVIR (State of Florida DOH Central Pharmacy), EPIVIR (ViiV Healthcare Company) |
| Generic |
|
| Formula |
C8H11N3O3S
|
| Exact mass |
229.0521
|
| Mol weight |
229.2562
|
| Structure |

     |
| Activity |
|
| Remark |
Same as: Therapeutic category: ATC code: |
| Comment |
Nucleoside reverse transcriptase inhibitor (NRTI)
|
| Target |
RNA-directed DNA polymerase inhibitor |
| Metabolism |
Transporter: SLC22A6 [HSA: 9356]
|
| Interaction |
|
| Pathway map |
|
| Structure map |
| Antiviral agents | | Anti-HIV agents |
|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D00353 Lamivudine (JAN/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
J05AF05 Lamivudine
D00353 Lamivudine (JAN/USP/INN)
USP drug classification [BR:br08302]
Antivirals
Antihepatitis Agents
Lamivudine
D00353 Lamivudine (JAN/USP/INN)
Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
Lamivudine
D00353 Lamivudine (JAN/USP/INN)
Antiinfectives [BR:br08307]
Antivirals
Anti-HBV agent
Reverse transcriptase inhibitor (RTI)
Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
Lamivudine [ATC:J05AF05]
D00353 Lamivudine (JAN/USP/INN)
Anti-HIV agent
Reverse transcriptase inhibitor (RTI)
Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
Lamivudine [ATC:J05AF05]
D00353 Lamivudine (JAN/USP/INN)
 |
| Other DBs |
CAS: 134678-17-4 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
| KCF data |
 ATOM 15
1 C1y C 43.8083 -23.2205
2 N4y N 45.2094 -22.5476
3 O2x O 42.6802 -22.4298
4 C1x C 43.3964 -24.5390
5 C8y C 46.3796 -21.8264
6 C8x C 43.9940 -21.8893
7 C1y C 41.5784 -23.2567
8 S2x S 42.0214 -24.5614
9 N5x N 46.3768 -20.3875
10 O5x O 47.5912 -22.4780
11 C8x C 43.9651 -20.5136
12 C1b C 40.3778 -22.6348
13 C8y C 45.1335 -19.7975
14 O1a O 39.0672 -23.4248
15 N1a N 45.0935 -18.4183
BOND 16
1 1 2 1 #Down
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 5 10 2
10 6 11 2
11 7 12 1 #Down
12 9 13 2
13 12 14 1
14 13 15 1
15 7 8 1
16 11 13 1
|