KEGG   DRUG: D00362Help
Entry
D00362                      Drug                                   

Name
Lisinopril hydrate (JP16);
Lisinopril (USP);
Lisinopril dihydrate;
Prinivil (TN);
Zestril (TN)
Product
  Generic
LISINOPRIL (Accord Healthcare), LISINOPRIL (Aidarex Pharmaceuticals LLC), LISINOPRIL (Aidarex Pharmaceuticals LLC), LISINOPRIL (Aidarex Pharmaceuticals LLC), LISINOPRIL (Aidarex Pharmaceuticals LLC), LISINOPRIL (American Health Packaging), LISINOPRIL (American Health Packaging), LISINOPRIL (Apotex Corp.), LISINOPRIL (Aurobindo Pharma Limited), LISINOPRIL (Blenheim Pharmacal), LISINOPRIL (Blenheim Pharmacal), LISINOPRIL (Blenheim Pharmacal), LISINOPRIL (Blenheim Pharmacal), LISINOPRIL (Blu Pharmaceuticals), LISINOPRIL (BluePoint Laboratories), LISINOPRIL (Bryant Ranch Prepack), LISINOPRIL (Bryant Ranch Prepack), LISINOPRIL (Bryant Ranch Prepack), LISINOPRIL (Camber Pharmaceuticals), LISINOPRIL (Cardinal Health), LISINOPRIL (Cardinal Health), LISINOPRIL (Cardinal Health), LISINOPRIL (Cardinal Health), LISINOPRIL (Cardinal Health), LISINOPRIL (Citron Pharma LLC), LISINOPRIL (Clinical Solutions Wholesale), LISINOPRIL (Contract Pharmacy Services-PA), LISINOPRIL (Contract Pharmacy Services-PA), LISINOPRIL (Dispensing Solutions), LISINOPRIL (Eon Labs), LISINOPRIL (H.J. Harkins Company), LISINOPRIL (Hikma Pharmaceutical), LISINOPRIL (IVAX Pharmaceuticals), LISINOPRIL (International Labs), LISINOPRIL (International Labs), LISINOPRIL (KAISER FOUNDATION HOSPITALS), LISINOPRIL (Keltman Pharmaceuticals), LISINOPRIL (Lake Erie Medical DBA Quality Care Products LLC), LISINOPRIL (Lake Erie Medical DBA Quality Care Products LLC), LISINOPRIL (Lake Erie Medical DBA Quality Care Products LLC), LISINOPRIL (Lake Erie Medical DBA Quality Care Products LLC), LISINOPRIL (Lake Erie Medical Quality Care Products LLC), LISINOPRIL (Legacy Pharmaceutical Packaging), LISINOPRIL (Legacy Pharmaceutical Packaging), LISINOPRIL (Life Line Home Care Services), LISINOPRIL (Lupin Pharmaceuticals), LISINOPRIL (Major Pharmaceuticals), LISINOPRIL (McKesson Contract Packaging), LISINOPRIL (McKesson Packaging Services a business unit of McKesson Corporation), LISINOPRIL (Mckesson Contract Packaging), LISINOPRIL (Med-Health Pharma), LISINOPRIL (MedVantx), LISINOPRIL (MedVantx), LISINOPRIL (MedVantx), LISINOPRIL (Mylan Institutional), LISINOPRIL (Mylan Pharmaceuticals), LISINOPRIL (NCS HealthCare of KY), LISINOPRIL (NCS HealthCare of KY), LISINOPRIL (NCS HealthCare of KY), LISINOPRIL (NCS HealthCare of KY), LISINOPRIL (NCS HealthCare of KY), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (PD-Rx Pharmaceuticals), LISINOPRIL (Physicians Total Care), LISINOPRIL (Preferred Pharmaceuticals), LISINOPRIL (Preferred Pharmaceuticals), LISINOPRIL (Preferred Pharmaceuticals), LISINOPRIL (Qualitest Pharmaceuticals), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (REMEDYREPACK), LISINOPRIL (Ranbaxy Pharmaceuticals), LISINOPRIL (Rebel Distributors Corp), LISINOPRIL (Rebel Distributors Corp), LISINOPRIL (RedPharm Drug), LISINOPRIL (RedPharm Drug), LISINOPRIL (RedPharm Drug), LISINOPRIL (STAT RX USA LLC), LISINOPRIL (STAT Rx USA LLC), LISINOPRIL (St Marys Medical Park Pharmacy), LISINOPRIL (St Marys Medical Park Pharmacy), LISINOPRIL (State of Florida DOH Central Pharmacy), LISINOPRIL (State of Florida DOH Central Pharmacy), LISINOPRIL (State of Florida DOH Central Pharmacy), LISINOPRIL (State of Florida DOH Central Pharmacy), LISINOPRIL (State of Florida DOH Central Pharmacy), LISINOPRIL (Unit Dose Services), LISINOPRIL (Unit Dose Services), LISINOPRIL (Unit Dose Services), LISINOPRIL (Unit Dose Services), LISINOPRIL (Unit Dose Services), LISINOPRIL (Unit Dose Services), LISINOPRIL (Watson Laboratories), LISINOPRIL (West-Ward Pharmaceutical Corp), LISINOPRIL (West-Ward Pharmaceutical Corp), LISINOPRIL (Wockhardt Limited), LISINOPRIL (Wockhardt USA LLC.)
Formula
C21H31N3O5. 2H2O
Exact mass
441.2475
Mol weight
441.5185
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
ATC code: 
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2144  Angiotensin converting enzyme inhibitors
     D00362  Lisinopril hydrate (JP16); Lisinopril (USP)
   217  Vasodilators
    2179  Others
     D00362  Lisinopril hydrate (JP16); Lisinopril (USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA03 Lisinopril
      D00362  Lisinopril hydrate (JP16); Lisinopril (USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin-converting Enzyme (ACE) Inhibitors
   Lisinopril
    D00362  Lisinopril hydrate (JP16); Lisinopril (USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
    Lisinopril [ATC:C09AA03]
     D00362  Lisinopril (USP)
BRITE hierarchy
Other DBs
CAS: 
83915-83-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        31
            1   N1y N    35.2006  -17.8564
            2   C1y C    36.3299  -18.6909
            3   C5a C    33.9897  -18.5524
            4   C1x C    35.6541  -16.5295
            5   C1x C    37.4720  -17.8812
            6   C6a C    36.3139  -20.0906
            7   C1c C    32.7788  -17.8504
            8   O5a O    33.9897  -19.9506
            9   C1x C    37.0595  -16.5467
            10  O6a O    37.5141  -20.8049
            11  O6a O    35.0922  -20.7744
            12  N1b N    31.5622  -18.5524
            13  C1b C    32.7788  -16.4524
            14  C1c C    30.3513  -17.8504
            15  C1b C    33.9897  -15.7564
            16  C1b C    29.1403  -18.5466
            17  C6a C    30.3513  -16.4524
            18  C1b C    33.9897  -14.3524
            19  C1b C    27.9294  -17.8504
            20  O6a O    31.5679  -15.7504
            21  O6a O    29.1403  -15.7504
            22  C1b C    32.7788  -13.6504
            23  C8y C    26.7185  -18.5466
            24  N1a N    31.5679  -14.3524
            25  C8x C    26.7185  -19.9447
            26  C8x C    25.5076  -17.8447
            27  C8x C    25.5076  -20.6466
            28  C8x C    24.2910  -18.5466
            29  C8x C    24.2910  -19.9447
            30  O0  O    41.5543  -17.3474
            31  O0  O    41.5543  -17.3474
BOND        30
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     6  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 1 #Up
            13   12  14 1
            14   13  15 1
            15   14  16 1
            16   14  17 1 #Up
            17   15  18 1
            18   16  19 1
            19   17  20 1
            20   17  21 2
            21   18  22 1
            22   19  23 1
            23   22  24 1
            24   23  25 1
            25   23  26 2
            26   25  27 2
            27   26  28 1
            28   27  29 1
            29    5   9 1
            30   28  29 2
BRACKET     1    39.6900  -18.2700   39.6900  -16.4500
            1    42.0000  -16.4500   42.0000  -18.2700
            1  2
 ORIGINAL  1   30
 REPEAT    1   31

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