| Entry |
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| Name |
Mazindol (JAN/USP/INN);
Sanorex (TN)
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| Formula |
C16H13ClN2O
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| Exact mass |
284.0716
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| Mol weight |
284.7402
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| Structure |
     |
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| Activity |
Anorexic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
noradrenalin transporter inhibitor [HSA: 6530] [KO: K05035]; dopamine transporter inhibitor [HSA: 6531] [KO: K05036]; serotonin transporter inhibitor [HSA: 6532] [KO: K05037] |
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| Pathway |
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| Interaction |
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| Structure map |
| Neurotransmitter transporter inhibitors |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
119 Miscellaneous
1190 Miscellaneous
D00367 Mazindol (JAN/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
A08AA Centrally acting antiobesity products
A08AA05 Mazindol
D00367 Mazindol (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (noradrenalin transporter) [HSA:6530] [KO:K05035]
Mazindol [ATC:A08AA05]
D00367 Mazindol (JAN/USP/INN)
SLC6A3 (dopamine transporter) [HSA:6531] [KO:K05036]
Mazindol [ATC:A08AA05]
D00367 Mazindol (JAN/USP/INN)
SLC6A4 (serotonin transporter) [HSA:6532] [KO:K05037]
Mazindol [ATC:A08AA05]
D00367 Mazindol (JAN/USP/INN)
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| Other DBs |
CAS: 22232-71-9 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 20
1 C1z C 26.5010 -18.0774
2 N1y N 27.3416 -16.9509
3 C8y C 25.1586 -17.6397
4 C8y C 26.5010 -19.4315
5 O1a O 27.9369 -18.5735
6 C2y C 26.5127 -15.7895
7 C1x C 28.6957 -16.5132
8 C8y C 25.1645 -16.2272
9 C8x C 23.9329 -18.3342
10 C8x C 25.3278 -20.0969
11 C8x C 27.6742 -20.0969
12 N2x N 27.3532 -14.6454
13 C1x C 28.7014 -15.0890
14 C8x C 23.9387 -15.5151
15 C8x C 22.7188 -17.6280
16 C8x C 25.3278 -21.4510
17 C8x C 27.6742 -21.4510
18 C8x C 22.7247 -16.2155
19 C8y C 26.5010 -22.1280
20 X Cl 26.5010 -23.5346
BOND 23
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 1
7 3 8 2
8 3 9 1
9 4 10 2
10 4 11 1
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 2
15 10 16 1
16 11 17 2
17 14 18 2
18 16 19 2
19 19 20 1
20 6 8 1
21 12 13 1
22 15 18 1
23 17 19 1
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