KEGG   DRUG: D00390Help
Entry
D00390                      Drug                                   

Name
Triflupromazine (USP/INN);
Vesprin (TN)
Formula
C18H19F3N2S
Exact mass
352.1221
Mol weight
352.4171
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
ATC code: 
Drug group: 
Comment
withdrawal drug
Target
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AA Phenothiazines with aliphatic side-chain
     N05AA05 Triflupromazine
      D00390  Triflupromazine (USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Triflupromazine
      D00390  Triflupromazine (USP/INN)
BRITE hierarchy
Other DBs
CAS: 
146-54-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8y C    22.1709  -18.3123
            2   N1y N    23.3692  -17.6226
            3   C8y C    22.1709  -19.7036
            4   C8x C    20.9432  -17.6226
            5   C8y C    24.5967  -18.3357
            6   C1b C    23.3692  -16.2196
            7   S2x S    23.3692  -20.3993
            8   C8x C    20.9432  -20.3993
            9   C8x C    19.7216  -18.3357
            10  C8y C    24.5967  -19.6802
            11  C8x C    25.8010  -17.6459
            12  C1b C    24.5967  -15.5240
            13  C8x C    19.7216  -19.6802
            14  C8x C    25.8010  -20.3876
            15  C8y C    27.0402  -18.3534
            16  C1b C    24.5967  -14.1211
            17  C8x C    27.0402  -19.6745
            18  N1c N    25.8010  -13.4489
            19  C1a C    25.8185  -12.0283
            20  C1a C    27.0402  -14.1328
            21  C1d C    28.2414  -17.6558
            22  X   F    29.4000  -16.9400
            23  X   F    28.9100  -18.8300
            24  X   F    27.5100  -16.4500
BOND        26
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    6  12 1
            12    8  13 2
            13   10  14 1
            14   11  15 2
            15   12  16 1
            16   14  17 2
            17   16  18 1
            18   18  19 1
            19   18  20 1
            20    7  10 1
            21    9  13 1
            22   15  17 1
            23   15  21 1
            24   21  22 1
            25   21  23 1
            26   21  24 1

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