| Entry |
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| Name |
Trifluridine (USP/INN);
Viroptic (TN)
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| Product |
|
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| Generic |
|
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| Formula |
C10H11F3N2O5
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| Exact mass |
296.062
|
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| Mol weight |
296.2
|
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| Structure |
     |
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| Activity |
Antiviral [ophthalmic] [DS: H00365]
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| Remark |
|
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| Target |
DNA polymerase inhibitor [EC: 2.7.7.7] |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD02 Trifluridine
D00391 Trifluridine (USP/INN)
USP drug classification [BR:br08302]
Antivirals
Antiherpetic Agents
Trifluridine
D00391 Trifluridine (USP/INN)
Antiinfectives [BR:br08307]
Antivirals
Anti-HSV agent
DNA polymerase inhibitor
Pyrimidine analogue
Trifluridine [ATC:S01AD02]
D00391 Trifluridine (USP/INN)
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| Other DBs |
CAS: 70-00-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 20
1 C1y C 22.3368 -20.5135
2 C1x C 23.6872 -20.5135
3 C1y C 24.1137 -19.2341
4 O2x O 23.0475 -18.3811
5 C1y C 21.9103 -19.2341
6 O1a O 21.5549 -21.6507
7 C1b C 20.6309 -18.8076
8 O1a O 19.6358 -19.7316
9 N4y N 25.4768 -18.8308
10 C8y C 26.5112 -19.8058
11 N4x N 27.8729 -19.3976
12 C8y C 28.2002 -18.0142
13 C8y C 27.1657 -17.0391
14 C8x C 25.8041 -17.4474
15 O5x O 26.1901 -21.1657
16 O5x O 29.5837 -17.5996
17 C1d C 27.4929 -15.6557
18 X F 27.8202 -14.2723
19 X F 26.1095 -15.3285
20 X F 28.8763 -15.9830
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1 #Down
7 5 7 1 #Up
8 7 8 1
9 3 9 1 #Up
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 2
15 9 14 1
16 10 15 2
17 12 16 2
18 13 17 1
19 17 18 1
20 17 19 1
21 17 20 1
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