KEGG   DRUG: TrimethadioneHelp
Entry
D00392                      Drug                                   

Name
Trimethadione (JP17/INN);
Tridione (TN)
Product
Formula
C6H9NO3
Exact mass
143.0582
Mol weight
143.1406
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02032  Oxazolidine antiepileptics
Cyp substrate
 DG01633  CYP3A substrate
Remark
Therapeutic category: 
ATC code: 
Activity
Antiepileptic
Comment
Oxazolidine derivative
Metabolism
Enzyme: CYP2C9 [HSA:1559], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AC Oxazolidine derivatives
     N03AC02 Trimethadione
      D00392  Trimethadione (JP17/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1133  Oxazolidines
     D00392  Trimethadione (JP17/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2C9
   Trimethadione
    D00392  Trimethadione (JP17/INN)
  CYP3A4
   Trimethadione
    D00392  Trimethadione (JP17/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00392  Trimethadione
Neurological agents [br08367.html]
 Antiepileptic agents
  D00392
BRITE hierarchy
Other DBs
CAS: 
127-48-0
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        10
            1   C1z C    21.1150  -16.4080
            2   C5x C    21.5533  -17.7404
            3   O7x O    22.2546  -15.5841
            4   C1a C    20.1216  -15.4088
            5   C1a C    19.8994  -17.0976
            6   N1y N    22.9499  -17.7404
            7   O5x O    20.7351  -18.8684
            8   C7x C    23.3883  -16.4080
            9   C1a C    23.7739  -18.8684
            10  O6a O    24.7148  -15.9815
BOND        10
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 2
            7     3   8 1
            8     6   9 1
            9     8  10 2
            10    6   8 1

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