| Entry |
|
|---|
| Name |
Trimipramine (USAN/INN)
|
|---|
| Formula |
C20H26N2
|
|---|
| Exact mass |
294.2096
|
|---|
| Mol weight |
294.4338
|
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| Structure |
     |
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| Activity |
Antidepressant
|
|---|
| Remark |
|
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| Comment |
Tricyclic antidepressants
|
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| Target |
noradrenalin transporter inhibitor [HSA: 6530] [KO: K05035]; serotonin transporter inhibitor [HSA: 6532] [KO: K05037] |
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
Genomic biomarker: CYP2D6 [HSA: 1565]
 |
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| Structure map |
| Antidepressants | | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA06 Trimipramine
D00394 Trimipramine (USAN/INN)
USP drug classification [BR:br08302]
Antidepressants
Tricyclics
Trimipramine
D00394 Trimipramine (USAN/INN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (noradrenalin transporter) [HSA:6530] [KO:K05035]
Trimipramine [ATC:N06AA06]
D00394 Trimipramine (USAN/INN)
 |
|---|
| Other DBs |
CAS: 739-71-9 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 22
1 C1x C 30.5200 -20.7200
2 C8y C 29.6800 -19.6000
3 C8y C 30.0300 -18.2700
4 N1y N 31.2900 -17.7100
5 C1x C 31.9200 -20.7200
6 C8y C 32.5500 -18.3400
7 C8y C 32.8300 -19.6700
8 C8x C 28.9800 -17.2900
9 C8x C 27.5800 -17.7100
10 C8x C 27.2300 -19.0400
11 C8x C 28.3500 -20.0200
12 C8x C 34.1600 -20.0900
13 C8x C 35.2100 -19.1800
14 C8x C 34.9300 -17.7800
15 C8x C 33.6000 -17.3600
16 C1b C 31.2900 -16.3100
17 C1c C 32.4800 -15.6100
18 C1b C 33.6700 -16.3100
19 C1a C 32.4800 -14.2100
20 N1c N 34.8600 -15.6100
21 C1a C 36.0500 -16.3100
22 C1a C 34.8600 -14.2100
BOND 24
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 17 19 1
22 18 20 1
23 20 21 1
24 20 22 1
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