KEGG   DRUG: D00397Help
Entry
D00397                      Drug                                   

Name
Tropicamide (JP16/USP/INN);
Mydriacyl (TN)
Product
  Generic
Formula
C17H20N2O2
Exact mass
284.1525
Mol weight
284.3529
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic [ophthalmic]
Remark
Therapeutic category: 
ATC code: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA06 Tropicamide
      D00397  Tropicamide (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1311  Mydriatic agents
     D00397  Tropicamide (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Tropicamide
      D00397  Tropicamide (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00397  Tropicamide
BRITE hierarchy
Other DBs
CAS: 
1508-75-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C1c C    24.0800  -21.3500
            2   C8y C    25.3400  -21.9800
            3   C5a C    22.8900  -22.0500
            4   C1b C    24.0800  -19.9500
            5   C8x C    26.5300  -21.2800
            6   C8x C    25.3400  -23.3800
            7   N1c N    21.7000  -21.3500
            8   O5a O    22.8900  -23.4500
            9   O1a O    25.3400  -19.2500
            10  C8x C    27.7200  -21.9800
            11  C8x C    26.5300  -24.0800
            12  C1b C    20.4400  -22.0500
            13  C1b C    21.7000  -19.9500
            14  C8x C    27.7200  -23.3800
            15  C8y C    19.2500  -21.3500
            16  C1a C    22.8900  -19.1800
            17  C8x C    19.2500  -19.9500
            18  C8x C    18.0600  -22.0500
            19  C8x C    18.0600  -19.2500
            20  C8x C    16.8000  -21.3500
            21  N5x N    16.8000  -19.8800
BOND        22
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 1
            13   10  14 2
            14   12  15 1
            15   13  16 1
            16   15  17 2
            17   15  18 1
            18   17  19 1
            19   18  20 2
            20   19  21 2
            21   11  14 1
            22   20  21 1

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