KEGG   DRUG: D00413Help
Entry
D00413                      Drug                                   

Name
Zidovudine (JP16/USP/INN);
Retrovir (TN)
Product
  Generic
Formula
C10H13N5O4
Exact mass
267.0968
Mol weight
267.2413
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00406]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
Target
RNA-directed DNA polymerase inhibitor
Metabolism
Enzyme: UGT2B7 [HSA:7364]
Transporter: SLC22A6 [HSA:9356], SLC22A8 [HSA:9376]
Interaction
Drug interaction
Structure map
Antiviral agents
Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF01 Zidovudine
      D00413  Zidovudine (JP16/USP/INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Zidovudine
    D00413  Zidovudine (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00413  Zidovudine (JP16/USP/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HIV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Zidovudine
      D00413  Zidovudine (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00413  Zidovudine
BRITE hierarchy
Other DBs
CAS: 
30516-87-1
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C1y C    21.8892  -16.1997
            2   N4y N    23.5794  -15.4271
            3   C1x C    21.4499  -17.5090
            4   O2x O    20.7758  -15.3833
            5   C8y C    24.7119  -14.7808
            6   C8x C    22.3375  -14.8245
            7   C1y C    20.0762  -17.5044
            8   C1y C    19.6569  -16.1923
            9   N4x N    24.7212  -13.3441
            10  O5x O    25.9172  -15.4428
            11  C8y C    22.3030  -13.4511
            12  N2b N    19.2710  -18.6180
            13  C1b C    18.3417  -15.7702
            14  C8y C    23.4879  -12.7321
            15  C1a C    21.0666  -12.8501
            16  O1a O    17.3143  -16.6825
            17  O5x O    23.5292  -11.3605
            18  N0  N    18.3631  -19.6938 #+
            19  N2a N    17.3740  -20.8595 #-
BOND        20
            1     1   2 1 #Up
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1 #Down
            12    8  13 1 #Up
            13    9  14 1
            14   11  15 1
            15   13  16 1
            16   14  17 2
            17    7   8 1
            18   11  14 1
            19   12  18 2
            20   18  19 2

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