KEGG   DRUG: D00421Help
Entry
D00421                      Drug                                   
Name
Ramipril (USP/INN);
Altace (TN)
Product
  Generic
Formula
C23H32N2O5
Exact mass
416.2311
Mol weight
416.5106
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive: Enzyme inhibitors [angiotensin-converting]
Remark
ATC code: 
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA05 Ramipril
      D00421  Ramipril (USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin-converting Enzyme (ACE) Inhibitors
   Ramipril
    D00421  Ramipril (USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
    Ramipril [ATC:C09AA05]
     D00421  Ramipril (USP/INN)
BRITE hierarchy
Other DBs
CAS: 
87333-19-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   N1y N    35.7418  -17.8028
            2   C1y C    37.0644  -18.2769
            3   C1y C    35.7891  -16.4054
            4   C5a C    34.5302  -18.5074
            5   C1y C    37.9147  -17.1669
            6   C1x C    37.8592  -19.4374
            7   C1x C    37.1260  -16.0118
            8   C1c C    33.3189  -17.8085
            9   O5a O    34.5302  -19.9053
            10  C1x C    39.2355  -17.6391
            11  C1x C    39.2716  -19.0378
            12  N1b N    32.1073  -18.5134
            13  C1a C    33.3246  -16.4108
            14  C1c C    30.8959  -17.8144
            15  C1b C    29.6903  -18.5191
            16  C7a C    30.8959  -16.4166
            17  C1b C    28.4789  -17.8318
            18  O7a O    32.1073  -15.7176
            19  O6a O    29.6786  -15.7176
            20  C8y C    27.2790  -18.5250
            21  C1b C    32.0956  -14.3081
            22  C8x C    27.2790  -19.9286
            23  C8x C    26.0676  -17.8318
            24  C1a C    30.8726  -13.6151
            25  C8x C    26.0676  -20.6275
            26  C8x C    24.8560  -18.5250
            27  C8x C    24.8560  -19.9286
            28  C6a C    35.7891  -15.0054
            29  O6a O    36.9978  -14.3074
            30  O6a O    34.5512  -14.2911
BOND        32
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11    8  12 1
            12    8  13 1 #Up
            13   12  14 1
            14   14  15 1
            15   14  16 1 #Up
            16   15  17 1
            17   16  18 1
            18   16  19 2
            19   17  20 1
            20   18  21 1
            21   20  22 1
            22   20  23 2
            23   21  24 1
            24   22  25 2
            25   23  26 1
            26   25  27 1
            27    5   7 1
            28   10  11 1
            29   26  27 2
            30    3  28 1 #Down
            31   28  29 1
            32   28  30 2

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