KEGG   DRUG: D00421Help
Entry
D00421                      Drug                                   

Name
Ramipril (USP/INN);
Altace (TN)
Product
  Generic
RAMIPRIL (Aidarex Pharmaceuticals LLC), RAMIPRIL (American Health Packaging), RAMIPRIL (Apotex Corp.), RAMIPRIL (Atlantic Biologicals Corps), RAMIPRIL (Aurobindo Pharma Limited), RAMIPRIL (BluePoint Laboratories), RAMIPRIL (Bryant Ranch Prepack), RAMIPRIL (Bryant Ranch Prepack), RAMIPRIL (Cadila Healthcare Limited), RAMIPRIL (Camber Pharmaceuticals), RAMIPRIL (Cardinal Health), RAMIPRIL (Cobalt Laboratories), RAMIPRIL (Dispensing Solutions), RAMIPRIL (Dr. Reddy's Laboratories Limited), RAMIPRIL (Exelan Pharmaceuticals), RAMIPRIL (Golden State Medical Supply), RAMIPRIL (Lake Erie Medical DBA Quality Care Products LLC), RAMIPRIL (Lupin Pharmaceuticals), RAMIPRIL (PD-Rx Pharmaceuticals), RAMIPRIL (PD-Rx Pharmaceuticals), RAMIPRIL (Physicians Total Care), RAMIPRIL (REMEDYREPACK), RAMIPRIL (Rebel Distributors Corp), RAMIPRIL (Roxane Laboratories), RAMIPRIL (Teva Pharmaceuticals USA), RAMIPRIL (Zydus Pharmaceuticals (USA))
Formula
C23H32N2O5
Exact mass
416.2311
Mol weight
416.5106
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive: Enzyme inhibitors [angiotensin-converting]
Remark
ATC code: 
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA05 Ramipril
      D00421  Ramipril (USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin-converting Enzyme (ACE) Inhibitors
   Ramipril
    D00421  Ramipril (USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
    Ramipril [ATC:C09AA05]
     D00421  Ramipril (USP/INN)
BRITE hierarchy
Other DBs
CAS: 
87333-19-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   N1y N    35.7418  -17.8028
            2   C1y C    37.0644  -18.2769
            3   C1y C    35.7891  -16.4054
            4   C5a C    34.5302  -18.5074
            5   C1y C    37.9147  -17.1669
            6   C1x C    37.8592  -19.4374
            7   C1x C    37.1260  -16.0118
            8   C1c C    33.3189  -17.8085
            9   O5a O    34.5302  -19.9053
            10  C1x C    39.2355  -17.6391
            11  C1x C    39.2716  -19.0378
            12  N1b N    32.1073  -18.5134
            13  C1a C    33.3246  -16.4108
            14  C1c C    30.8959  -17.8144
            15  C1b C    29.6903  -18.5191
            16  C7a C    30.8959  -16.4166
            17  C1b C    28.4789  -17.8318
            18  O7a O    32.1073  -15.7176
            19  O6a O    29.6786  -15.7176
            20  C8y C    27.2790  -18.5250
            21  C1b C    32.0956  -14.3081
            22  C8x C    27.2790  -19.9286
            23  C8x C    26.0676  -17.8318
            24  C1a C    30.8726  -13.6151
            25  C8x C    26.0676  -20.6275
            26  C8x C    24.8560  -18.5250
            27  C8x C    24.8560  -19.9286
            28  C6a C    35.7891  -15.0054
            29  O6a O    36.9978  -14.3074
            30  O6a O    34.5512  -14.2911
BOND        32
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11    8  12 1
            12    8  13 1 #Up
            13   12  14 1
            14   14  15 1
            15   14  16 1 #Up
            16   15  17 1
            17   16  18 1
            18   16  19 2
            19   17  20 1
            20   18  21 1
            21   20  22 1
            22   20  23 2
            23   21  24 1
            24   22  25 2
            25   23  26 1
            26   25  27 1
            27    5   7 1
            28   10  11 1
            29   26  27 2
            30    3  28 1 #Down
            31   28  29 1
            32   28  30 2

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