KEGG   DRUG: D00432Help
Entry
D00432                      Drug                                   

Name
Nadolol (JP16/USP/INN);
Corgard (TN)
Product
  Generic
Formula
C17H27NO4
Exact mass
309.194
Mol weight
309.4006
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Remark
Therapeutic category: 
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
Antimigraines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA12 Nadolol
      D00432  Nadolol (JP16/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Nadolol
    D00432  Nadolol (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D00432  Nadolol (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Nadolol
      D00432  Nadolol (JP16/USP/INN)
    beta2-adrenergic receptor
     Nadolol
      D00432  Nadolol (JP16/USP/INN)
    beta3-adrenergic receptor
     Nadolol
      D00432  Nadolol (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00432  Nadolol
BRITE hierarchy
Other DBs
CAS: 
42200-33-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    19.1100  -15.8200
            2   C8y C    17.9200  -15.1200
            3   C8y C    20.3700  -15.1200
            4   C1x C    19.1100  -17.2200
            5   C1x C    16.7300  -15.8200
            6   C8x C    17.9200  -13.7200
            7   C8x C    20.3700  -13.7200
            8   O2a O    21.5600  -15.8200
            9   C1y C    17.9200  -17.9200
            10  C1y C    16.7300  -17.2200
            11  C8x C    19.1100  -13.0200
            12  C1b C    22.7500  -15.1200
            13  O1a O    17.9200  -19.3200
            14  O1a O    15.4700  -17.9200
            15  C1c C    24.0100  -15.8200
            16  C1b C    25.2000  -15.1200
            17  O1a O    24.0100  -17.2200
            18  N1b N    26.3900  -15.8200
            19  C1d C    27.6500  -15.1200
            20  C1a C    28.8400  -15.8200
            21  C1a C    27.6500  -13.9300
            22  C1a C    28.8624  -14.4200
BOND        23
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    6  11 2
            11    8  12 1
            12    9  13 1 #Down
            13   10  14 1 #Down
            14   12  15 1
            15   15  16 1
            16   15  17 1
            17   16  18 1
            18   18  19 1
            19   19  20 1
            20   19  21 1
            21    7  11 1
            22    9  10 1
            23   19  22 1

» Japanese version   » Back

DBGET integrated database retrieval system