| Entry |
|
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| Name |
Quinapril hydrochloride (JP16/USP);
Accupril (TN)
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| Product |
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| Generic |
QUINAPRIL (AvKARE), QUINAPRIL (Bryant Ranch Prepack), QUINAPRIL (Bryant Ranch Prepack), QUINAPRIL (Camber Pharmaceuticals), QUINAPRIL (Dr.Reddy's Laboratories Limited), QUINAPRIL (Lupin Pharmaceuticals), QUINAPRIL (Physicians Total Care), QUINAPRIL (Ranbaxy Pharmaceutical), QUINAPRIL (Rebel Distributors Corp), QUINAPRIL (Sun Pharmaceutical Industries Limited), QUINAPRIL (Aurobindo Pharma Limited), QUINAPRIL HYDROCHLORIDE (Greenstone LLC), QUINAPRIL HYDROCHLORIDE (Mylan Pharmaceuticals), QUINAPRIL HYDROCHLORIDE (PD-Rx Pharmaceuticals) |
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| Formula |
C25H30N2O5. HCl
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| Exact mass |
474.1922
|
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| Mol weight |
474.977
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| Structure |
     |
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| Activity |
Antihypertensive;
Enzyme inhibitor [angiotensin-converting]
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Target |
angiotensin-converting enzyme (ACE) inhibitor [HSA: 1636] [KO: K01283] |
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| Pathway |
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| Interaction |
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| Structure map |
| Renin-angiotensin system inhibitors |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2144 Angiotensin converting enzyme inhibitors
D00459 Quinapril hydrochloride (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA06 Quinapril
D00459 Quinapril hydrochloride (JP16/USP)
USP drug classification [BR:br08302]
Cardiovascular Agents
Angiotensin-converting Enzyme (ACE) Inhibitors
Quinapril
D00459 Quinapril hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases
angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
Quinapril [ATC:C09AA06]
D00459 Quinapril hydrochloride (JP16/USP)
 |
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| Other DBs |
CAS: 82586-55-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 33
1 C1x C 28.2490 -19.8211
2 C8y C 29.4582 -19.1183
3 N1y N 27.0337 -19.1187
4 C8y C 29.4645 -17.7270
5 C8x C 30.6604 -19.8200
6 C1y C 27.0378 -17.7192
7 C1x C 28.2493 -17.0245
8 C8x C 30.6680 -17.0343
9 C8x C 31.8720 -19.1253
10 C8x C 31.8732 -17.7311
11 N1b N 23.4099 -19.8234
12 C1c C 22.1992 -19.1275
13 C7a C 22.1933 -17.7238
14 C1b C 20.9826 -19.8351
15 O7a O 23.4099 -17.0219
16 O6a O 20.9709 -17.0277
17 C1b C 19.7661 -19.1450
18 C1b C 23.4040 -15.6182
19 C8y C 18.5554 -19.8351
20 C1a C 22.1875 -14.9223
21 C8x C 18.5554 -21.2506
22 C8x C 17.3506 -19.1450
23 C8x C 17.3506 -21.9582
24 C8x C 16.1282 -19.8351
25 C8x C 16.1282 -21.2506
26 C1c C 24.6167 -19.1187
27 C5a C 25.8252 -19.8183
28 O5a O 25.8252 -21.2177
29 C1a C 24.6140 -17.7194
30 C6a C 27.0266 -16.3129
31 O6a O 28.2329 -15.6036
32 O6a O 25.8093 -15.6229
33 X Cl 30.5428 -21.2516
BOND 34
1 8 10 2
2 6 7 1
3 9 10 1
4 11 12 1
5 12 13 1 #Up
6 12 14 1
7 13 15 1
8 13 16 2
9 14 17 1
10 15 18 1
11 17 19 1
12 18 20 1
13 19 21 1
14 19 22 2
15 21 23 2
16 22 24 1
17 23 25 1
18 24 25 2
19 1 2 1
20 11 26 1
21 1 3 1
22 26 27 1
23 27 3 1
24 2 4 2
25 27 28 2
26 2 5 1
27 26 29 1 #Up
28 3 6 1
29 6 30 1 #Down
30 4 7 1
31 30 31 1
32 4 8 1
33 30 32 2
34 5 9 2
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