KEGG   DRUG: D00461Help
Entry
D00461                      Drug                                   

Name
Quinethazone (JAN/INN);
Hydromox (TN)
Formula
C10H12ClN3O3S
Exact mass
289.0288
Mol weight
289.7386
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic
Remark
Same as: 
ATC code: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
    C03BA Sulfonamides, plain
     C03BA02 Quinethazone
      D00461  Quinethazone (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3 [HSA:6559] [KO:K14426] [TC:2.A.30.4.2]
     Quinethazone [ATC:C03BA02]
      D00461  Quinethazone (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
73-49-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8y C    25.3928  -19.8397
            2   C8y C    25.3928  -18.4507
            3   N1x N    26.6008  -20.5341
            4   C8x C    24.1788  -20.5341
            5   C8x C    24.1788  -17.7504
            6   C5x C    26.6008  -17.7504
            7   C1y C    27.8088  -19.8397
            8   C8y C    22.9650  -19.8397
            9   C8y C    22.9650  -18.4507
            10  N1x N    27.8088  -18.4507
            11  O5x O    26.6008  -16.3322
            12  C1b C    29.0343  -20.5341
            13  X   Cl   21.7453  -20.5341
            14  S4a S    21.7453  -17.7504
            15  C1a C    30.2423  -19.8221
            16  N1a N    20.5315  -17.0442
            17  O3c O    21.0450  -18.9642
            18  O3c O    22.4515  -16.5307
BOND        19
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 2
            9     6  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    9  14 1
            14   12  15 1
            15   14  16 1
            16   14  17 2
            17   14  18 2
            18    7  10 1
            19    8   9 1

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