| Entry |
|
| Name |
Oxaprozin (JP16/USAN/INN);
Daypro (TN)
|
| Product |
|
| Generic |
OXAPROZIN (Apotex Corp.), OXAPROZIN (Bryant Ranch Prepack), OXAPROZIN (Caraco Pharmaceutical Laboratories), OXAPROZIN (Dr. Reddy's Laboratories Limited), OXAPROZIN (Eon Labs), OXAPROZIN (Greenstone LLC), OXAPROZIN (H.J. Harkins Company), OXAPROZIN (Lake Erie Medical DBA Quality Care Products LLC), OXAPROZIN (PD-Rx Pharmaceuticals), OXAPROZIN (Physicians Total Care), OXAPROZIN (Preferred Pharmaceuticals), OXAPROZIN (Rebel Distributors Corp), OXAPROZIN (STAT RX USA LLC), OXAPROZIN (Teva Pharmaceuticals USA), OXAPROZIN (Unit Dose Services) |
| Formula |
C18H15NO3
|
| Exact mass |
293.1052
|
| Mol weight |
293.3166
|
| Structure |

     |
| Activity |
|
| Remark |
Same as: Therapeutic category: ATC code: |
| Target |
cyclooxygenase-1 (COX-1) inhibitor [HSA: 5742] [KO: K00509]; cyclooxygenase-2 (COX-2) inhibitor [HSA: 5743] [KO: K11987] |
| Pathway |
|
| Interaction |
|
| Structure map |
| 1,2-Diphenyl substitution family | | Cyclooxygenase inhibitors |
|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D00463 Oxaprozin (JP16/USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE12 Oxaprozin
D00463 Oxaprozin (JP16/USAN/INN)
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Oxaprozin
D00463 Oxaprozin (JP16/USAN/INN)
Anti-inflammatory Agents
Nonsteroidal Anti-inflammatory Drugs
Oxaprozin
D00463 Oxaprozin (JP16/USAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
Oxaprozin [ATC:M01AE12]
D00463 Oxaprozin (JP16/USAN/INN)
cyclooxygenase-2 (COX-2) [HSA:5743] [KO:K11987]
Oxaprozin [ATC:M01AE12]
D00463 Oxaprozin (JP16/USAN/INN)
 |
| Other DBs |
CAS: 21256-18-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
| KCF data |
 ATOM 22
1 C8y C 25.8557 -17.0142
2 C1b C 27.2577 -17.0142
3 N5x N 25.0145 -15.8927
4 C8y C 23.7060 -16.3132
5 C8y C 23.7060 -17.7152
6 O2x O 25.0145 -18.1358
7 C8x C 20.0609 -14.2103
8 C8x C 20.0609 -15.6123
9 C8x C 21.2760 -16.3132
10 C8y C 22.4910 -15.6123
11 C8x C 22.4910 -14.2103
12 C8x C 21.2760 -13.5093
13 C8x C 20.0609 -18.4162
14 C8x C 20.0609 -19.8181
15 C8x C 21.2760 -20.5191
16 C8x C 22.4910 -19.8181
17 C8y C 22.4910 -18.4162
18 C8x C 21.2760 -17.7152
19 C1b C 27.9586 -15.8000
20 C6a C 29.3606 -15.8000
21 O6a O 30.0620 -14.5852
22 O6a O 30.0612 -17.0135
BOND 24
1 1 2 1
2 1 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 7 8 2
8 8 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 7 12 1
13 10 4 1
14 13 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 13 18 1
20 17 5 1
21 2 19 1
22 19 20 1
23 20 21 1
24 20 22 2
|