KEGG   DRUG: D00514Help
Entry
D00514                      Drug                                   

Name
Dexmedetomidine (USAN/INN);
Dexdor (TN);
Precedex (TN)
Formula
C13H16N2
Exact mass
200.1313
Mol weight
200.2795
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Tranquilizer
Remark
Same as: 
ATC code: 
Target
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CM Other hypnotics and sedatives
     N05CM18 Dexmedetomidine
      D00514  Dexmedetomidine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
     Dexmedetomidine [ATC:N05CM18]
      D00514  Dexmedetomidine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
113775-47-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   C8y C    21.8688  -21.7213
            2   C1c C    23.0601  -20.9504
            3   C8y C    20.6775  -20.9504
            4   C8x C    21.8688  -23.0527
            5   C8y C    24.3214  -21.7213
            6   C1a C    23.0601  -19.5490
            7   C8y C    19.4162  -21.7213
            8   C1a C    20.6075  -19.5490
            9   C8x C    20.6775  -23.7534
            10  C8x C    24.3214  -23.1228
            11  N5x N    25.5828  -21.2307
            12  C8x C    19.4162  -23.1228
            13  C1a C    18.2249  -21.0205
            14  N4x N    25.6528  -23.4731
            15  C8x C    26.4236  -22.3519
BOND        16
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1 #Down
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    7  12 2
            12    7  13 1
            13   10  14 1
            14   11  15 2
            15    9  12 1
            16   14  15 1

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