| Entry |
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| Name |
Candesartan (USAN/INN)
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| Formula |
C24H20N6O3
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| Exact mass |
440.1597
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| Mol weight |
440.454
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| Structure |
     |
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| Activity |
Antagonist [angiotensin II receptor];
Antihypertensive
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| Remark |
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| Target |
angiotensin II receptor type 1 (AT1) antagonist [HSA: 185] [KO: K04166] |
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| Pathway |
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| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
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| Interaction |
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| Structure map |
| Angiotensin receptor and endothelin receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09C ANGIOTENSIN II ANTAGONISTS, PLAIN
C09CA Angiotensin II antagonists, plain
C09CA06 Candesartan
D00522 Candesartan (USAN/INN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Angiotensin II Receptor Antagonists
Candesartan
D00522 Candesartan (USAN/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Angiotensin
angiotensin II stimulates angiotensin subtype 1 (AT1) receptor [HSA:185] [KO:K04166]
Candesartan [ATC:C09CA06]
D00522 Candesartan (USAN/INN)
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| Other DBs |
CAS: 139481-59-7 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 33
1 C8y C 22.0850 -15.5109
2 N4y N 21.6416 -14.1867
3 C8y C 23.4790 -15.5166
4 C8y C 21.3850 -16.7182
5 C8y C 22.7790 -13.3526
6 C1b C 20.4167 -13.4984
7 N5x N 23.9165 -14.1867
8 C8x C 24.1731 -16.7241
9 C8x C 22.0790 -17.9257
10 C6a C 20.6733 -17.9199
11 O2a O 22.7790 -11.9526
12 C8y C 19.2150 -14.2217
13 C8x C 23.4731 -17.9316
14 O6a O 19.2733 -17.9082
15 O6a O 21.3557 -19.1331
16 C1b C 23.9922 -11.2526
17 C8x C 17.9842 -13.5392
18 C8x C 19.2441 -15.5984
19 C1a C 23.9922 -9.8526
20 C8x C 16.7826 -14.2625
21 C8x C 18.0309 -16.3450
22 C8y C 16.8176 -15.6625
23 C8y C 15.6102 -16.3799
24 C8y C 14.3794 -15.7032
25 C8x C 15.6335 -17.7798
26 C8y C 14.3560 -14.2975
27 C8x C 13.1836 -16.4208
28 C8x C 14.4318 -18.5032
29 N4x N 13.2243 -13.4925
30 N5x N 15.4877 -13.4517
31 C8x C 13.2127 -17.8265
32 N5x N 13.6327 -12.1509
33 N5x N 15.0326 -12.1277
BOND 37
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 4 10 1
10 5 11 1
11 6 12 1
12 8 13 2
13 10 14 1
14 10 15 2
15 11 16 1
16 12 17 1
17 12 18 2
18 16 19 1
19 17 20 2
20 18 21 1
21 20 22 1
22 22 23 1
23 23 24 1
24 23 25 2
25 24 26 1
26 24 27 2
27 25 28 1
28 26 29 1
29 26 30 2
30 27 31 1
31 29 32 1
32 30 33 1
33 5 7 2
34 9 13 1
35 21 22 2
36 28 31 2
37 32 33 2
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