| Entry |
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| Name |
Pilocarpine (JAN/USP);
Ocusert pilo-20 (TN)
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| Formula |
C11H16N2O2
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| Exact mass |
208.1212
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| Mol weight |
208.2569
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| Structure |
     |
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| Source |
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| Activity |
Antiglaucoma agent;
Cholinergic [ophthalmic] [DS: H00612]
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| Remark |
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| Target |
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| Pathway |
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| Metabolism |
Enzyme: CYP2A6 [HSA: 1548]
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| Interaction |
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| Structure map |
| Cholinergic and anticholinergic drugs |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07A PARASYMPATHOMIMETICS
N07AX Other parasympathomimetics
N07AX01 Pilocarpine
D00525 Pilocarpine (JAN/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB01 Pilocarpine
D00525 Pilocarpine (JAN/USP)
USP drug classification [BR:br08302]
Dental and Oral Agents
Pilocarpine
D00525 Pilocarpine (JAN/USP)
Ophthalmic Agents
Ophthalmic Antiglaucoma Agents
Cholinergic Agonists, Ophthalmic
Pilocarpine
D00525 Pilocarpine (JAN/USP)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
Pilocarpine [ATC:N07AX01 S01EB01]
D00525 Pilocarpine (JAN/USP)
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| Other DBs |
CAS: 92-13-7 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 15
1 C1y C 24.1199 -19.7000
2 C1y C 22.7112 -19.7000
3 C1b C 25.3415 -20.3431
4 C1x C 24.5641 -18.3555
5 C7x C 22.2729 -18.3555
6 C1b C 21.8810 -20.8399
7 C8y C 26.4112 -19.7058
8 O7x O 23.4185 -17.5255
9 O6a O 20.9284 -17.9171
10 C1a C 20.4782 -20.8338
11 N4y N 27.8257 -19.7058
12 C8x C 25.9670 -18.3614
13 C8x C 28.2584 -18.3614
14 C1a C 28.6499 -20.8456
15 N5x N 27.1186 -17.5313
BOND 16
1 1 2 1
2 1 3 1 #Down
3 1 4 1
4 2 5 1
5 2 6 1 #Down
6 3 7 1
7 4 8 1
8 5 9 2
9 6 10 1
10 7 11 1
11 7 12 2
12 11 13 1
13 11 14 1
14 12 15 1
15 5 8 1
16 13 15 2
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