KEGG   DRUG: D00535Help
Entry
D00535                      Drug                                   

Name
Vigabatrin (JAN/USAN/INN);
Sabril (TN)
Product
Formula
C6H11NO2
Exact mass
129.079
Mol weight
129.157
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticonvulsant [tardive dyskinesia]
Remark
Same as: 
ATC code: 
Target
GABA transaminase inhibitor [HSA:18] [KO:K13524]
  Pathway
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00280  Valine, leucine and isoleucine degradation
hsa00410  beta-Alanine metabolism
hsa00640  Propanoate metabolism
hsa00650  Butanoate metabolism
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Structure map
Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AG Fatty acid derivatives
     N03AG04 Vigabatrin
      D00535  Vigabatrin (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Vigabatrin
    D00535  Vigabatrin (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases
   GABA transaminase [HSA:18] [KO:K13524]
    Vigabatrin [ATC:N03AG04]
     D00535  Vigabatrin (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
60643-86-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        9
            1   C1c C    23.6410  -19.0753
            2   C1b C    24.8557  -18.3746
            3   C2b C    22.4264  -18.3805
            4   N1a N    23.6469  -20.4768
            5   C1b C    26.0703  -19.0636
            6   C2a C    21.2119  -19.0812
            7   C6a C    27.2850  -18.3688
            8   O6a O    28.4938  -19.0579
            9   O6a O    27.2791  -16.9614
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     5   7 1
            7     7   8 1
            8     7   9 2

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