KEGG   DRUG: Vigabatrin
Entry
D00535                      Drug                                   
Name
Vigabatrin (JAN/USP/INN);
Sabril (TN)
Product
  Generic
Formula
C6H11NO2
Exact mass
129.079
Mol weight
129.157
Structure
Simcomp
Class
Neuropsychiatric agent
 DG03199  Antiepileptic agent
  DG02037  GABA mimetic antiepileptic
Remark
Same as: C07500
Therapeutic category: 1139
ATC code: N03AG04
Product: D00535<JP/US>
Efficacy
Anticonvulsant, Antiepileptic
  Disease
Infantile spasms [DS:H01460]
Comment
Fatty acid derivative
Target
ABAT [HSA:18] [KO:K13524]
  Pathway
hsa04727  GABAergic synapse
Interaction
Structure map
map07033  Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AG Fatty acid derivatives
     N03AG04 Vigabatrin
      D00535  Vigabatrin (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   GABA Agents, Other
    Vigabatrin
     D00535  Vigabatrin (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D00535  Vigabatrin (JAN/USP/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   DG02037  GABA mimetic antiepileptic
    D00535  Vigabatrin
Drug classes [BR:br08332]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   D00535  Vigabatrin
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases (EC2)
   Aminotransferase
    ABAT
     D00535  Vigabatrin (JAN/USP/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00535
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00535
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00535
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00535
Other DBs
CAS: 60643-86-9
PubChem: 7847601
ChEBI: 63638
LigandBox: D00535
NIKKAJI: J82.341D
KCF data

ATOM        9
            1   C1c C    17.4113  -16.5555
            2   C1b C    18.6260  -15.8548
            3   N1a N    16.1967  -15.8607
            4   C2b C    17.4172  -17.9570
            5   C1b C    19.8406  -16.5438
            6   C6a C    21.0553  -15.8490
            7   O6a O    22.2641  -16.5381
            8   O6a O    21.0494  -14.4416
            9   C2a C    16.2033  -18.6648
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     5   6 1
            6     6   7 1
            7     6   8 2
            8     4   9 2

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