KEGG   DRUG: D00539Help
Entry
D00539                      Drug                                   

Name
Ethosuximide (JP16/USP/INN);
Zarontin (TN)
Product
  Generic
Formula
C7H11NO2
Exact mass
141.079
Mol weight
141.1677
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticonvulsant [DS:H00810]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Target
calcium channel T type blocker [HSA:8911 8912 8913] [KO:K04856 K04855 K04854]
  Pathway
hsa04010  MAPK signaling pathway
hsa04020  Calcium signaling pathway  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP2E1 [HSA:1571]
Interaction
Drug interaction
Structure map
Anticonvulsants
Calcium channel blocking drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D00539  Ethosuximide (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AD Succinimide derivatives
     N03AD01 Ethosuximide
      D00539  Ethosuximide (JP16/USP/INN)
USP drug classification [BR:br08302]
 Anticonvulsants
  Calcium Channel Modifying Agents
   Ethosuximide
    D00539  Ethosuximide (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Ca2+ channel, CACN alpha-1, CaVx.x
    calcium channel T type [HSA:8911 8912 8913] [KO:K04856 K04855 K04854]
     Ethosuximide [ATC:N03AD01]
      D00539  Ethosuximide (JP16/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
77-67-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        10
            1   C1z C    30.2572  -15.7833
            2   C5x C    31.0718  -14.6371
            3   C1x C    28.9189  -15.3703
            4   C1b C    31.5607  -16.2779
            5   C1a C    29.4311  -16.9121
            6   N1x N    30.2341  -13.5199
            7   O5x O    32.4683  -14.6255
            8   C5x C    28.9016  -13.9681
            9   C1a C    31.5774  -17.6569
            10  O5x O    27.7611  -13.1534
BOND        10
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 2
            7     3   8 1
            8     4   9 1
            9     8  10 2
            10    6   8 1

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