KEGG   DRUG: D00540Help
Entry
D00540                      Drug                                   

Name
Glycopyrronium bromide (JAN/INN);
Glycopyrrolate (USP);
Robinul (TN);
Seebri breezhaler (TN)
Product
  Generic
GLYCOPYRROLATE (American Health Packaging), GLYCOPYRROLATE (American Regent), GLYCOPYRROLATE (Aurolife Pharma), GLYCOPYRROLATE (Bryant Ranch Prepack), GLYCOPYRROLATE (Cardinal Health), GLYCOPYRROLATE (Cardinal Health), GLYCOPYRROLATE (Carilion Materials Management), GLYCOPYRROLATE (Dr. Reddy's Laboratories Limited), GLYCOPYRROLATE (Excellium Pharmaceutical), GLYCOPYRROLATE (General Injectables & Vaccines), GLYCOPYRROLATE (NCS HealthCare of KY), GLYCOPYRROLATE (Nexgen Pharma), GLYCATE (Nuro Pharma), GLYCOPYRROLATE (Par Pharmaceutical), GLYCOPYRROLATE (Qualitest Pharmaceuticals), GLYCOPYRROLATE (REMEDYREPACK), GLYCOPYRROLATE (REMEDYREPACK), GLYCOPYRROLATE (Ranbaxy Pharmaceuticals), GLYCOPYRROLATE (Rising Pharmaceuticals), GLYCOPYRROLATE (UDL Laboratories), GLYCOPYRROLATE (United Research Laboratories), GLYCOPYRROLATE (West-Ward Pharmaceutical Corp), GLYCOPYRROLATE (West-ward Pharmaceutical Corp)
  Other
Formula
C19H28NO3. Br
Exact mass
397.1253
Mol weight
398.3345
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
Therapeutic category: 
ATC code: 
Target
muscarinic cholinergic receptor M3 antagonist [HSA:1131] [KO:K04131]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AB Synthetic anticholinergics, quaternary ammonium compounds
     A03AB02 Glycopyrronium
      D00540  Glycopyrronium bromide (JAN/INN); Glycopyrrolate (USP)
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BB Anticholinergics
     R03BB06 Glycopyrronium bromide
      D00540  Glycopyrronium bromide (JAN/INN); Glycopyrrolate (USP)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Glycopyrrolate
    D00540  Glycopyrronium bromide (JAN/INN); Glycopyrrolate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D00540  Glycopyrronium bromide (JAN/INN); Glycopyrrolate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Glycopyrronium
      D00540  Glycopyrronium bromide (JAN/INN); Glycopyrrolate (USP)
BRITE hierarchy
Other DBs
CAS: 
596-51-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1d C    24.1031  -22.1674
            2   C7a C    22.9701  -22.8047
            3   O7a O    21.7662  -22.1674
            4   O6a O    22.9701  -24.2210
            5   C1y C    20.4915  -22.8756
            6   C1x C    19.4128  -22.0966
            7   C1x C    20.0908  -24.2414
            8   N2y N    18.2555  -22.8879 #+
            9   C1x C    18.7293  -24.2018
            10  C1y C    25.3216  -22.8892
            11  C1x C    25.7607  -24.2172
            12  C1x C    27.1619  -24.2138
            13  C1x C    27.5915  -22.8800
            14  C1x C    26.4559  -22.0593
            15  C8y C    24.1031  -20.7511
            16  C8x C    25.3296  -20.0429
            17  C8x C    25.3296  -18.6266
            18  C8x C    24.1031  -17.9184
            19  C8x C    22.8766  -18.6266
            20  C8x C    22.8766  -20.0429
            21  O1a O    25.1880  -21.3176
            22  C1a C    17.0289  -22.1798
            23  C1a C    17.0289  -23.5960
            24  X   Br   17.5880  -25.3541 #-
BOND        25
            1     1   2 1
            2     2   3 1
            3     2   4 2
            4     3   5 1
            5     5   6 1
            6     5   7 1
            7     6   8 1
            8     7   9 1
            9     8   9 1
            10    1  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   10  14 1
            16    1  15 1
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   15  20 2
            23    1  21 1
            24    8  22 1
            25    8  23 1

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