KEGG   DRUG: CarbidopaHelp
Entry
D00558                      Drug                                   

Name
Carbidopa (USP);
Carbidopa hydrate (JP17);
Lodosyn (TN)
Product
  Generic
Formula
C10H14N2O4. H2O
Exact mass
244.1059
Mol weight
244.2444
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01967  Antiparkinson agent
Other
 DG01617  Catecholamine synthesis inhibitors
Activity
Antiparkinsonian (potentiator), Decarboxylase inhibitor
Comment
Peripheral aromatic L-amino acid decarboxylase inhibitors (DCI)
Target
DDC [HSA:1644] [KO:K01593]
  Pathway
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Serotonergic synapse
Dopaminergic synapse
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Dopamine Precursors/L-Amino Acid Decarboxylase Inhibitors
   Carbidopa
    D00558  Carbidopa (USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases
   aromatic-L-amino-acid decarboxylase
    Carbidopa
     D00558  Carbidopa (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00558  Carbidopa hydrate
Neurological agents [br08367.html]
 Antiparkinson agents
  D00558
BRITE hierarchy
Other DBs
CAS: 
38821-49-7
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   O0  O    24.5218  -16.1191
            2   C8y C    14.0190  -16.1917
            3   C8y C    14.0190  -17.5936
            4   C8x C    15.2106  -18.2946
            5   C8x C    16.4723  -17.5936
            6   C8y C    16.4723  -16.1917
            7   C8x C    15.2106  -15.4907
            8   O1a O    12.8273  -15.4907
            9   O1a O    12.8273  -18.2946
            10  C1b C    17.6640  -15.4907
            11  C1d C    18.8556  -16.1917
            12  C6a C    20.0473  -15.4907
            13  O6a O    21.2389  -16.1917
            14  O6a O    20.0473  -14.0888
            15  N1b N    19.5556  -17.4041
            16  C1a C    17.8657  -17.1816
            17  N1a N    20.9298  -17.4046
BOND        16
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     2   8 1
            8     3   9 1
            9     6  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   12  14 2
            14   11  15 1 #Up
            15   11  16 1 #Down
            16   15  17 1

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