| Entry |
|
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| Name |
Goserelin acetate (JAN/USP);
Zoladex (TN)
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| Product |
|
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| Formula |
C59H84N18O14. C2H4O2
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| Exact mass |
1328.6626
|
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| Mol weight |
1329.4624
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| Structure |
     |
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| Activity |
|
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| Remark |
Therapeutic category: ATC code: |
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| Comment |
Goserelin cause downregulation of gonadotropin-releasing hormone (GnRH) receptor.
|
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| Target |
gonadotropin-releasing hormone (GnRH) receptor agonist [HSA: 2798] [KO: K04280] |
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| Pathway |
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| Interaction |
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| Structure map |
| Antineoplastics - hormones |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
249 Miscellaneous
2499 Others
D00573 Goserelin acetate (JAN/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AE Gonadotropin releasing hormone analogues
L02AE03 Goserelin
D00573 Goserelin acetate (JAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Gonadotropin-releasing hormone
gonadotropin-releasing hormone (GnRH) receptor [HSA:2798] [KO:K04280]
Goserelin [ATC:L02AE03]
D00573 Goserelin acetate (JAN)
Antineoplastics [BR:br08308]
Hormones and hormone antagonist
Lutenizing hormone-releasing hormone agonist
Goserelin [ATC:L02AE03]
D00573 Goserelin acetate (JAN)
 |
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| Other DBs |
CAS: 145781-92-6 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 95
1 C8y C 21.8333 -13.6442
2 C8y C 22.2780 -12.3294
3 C1b C 20.6321 -14.3443
4 C8x C 22.9592 -14.4768
5 C8y C 23.6589 -12.3387
6 C8x C 21.5969 -11.1186
7 C1c C 20.6321 -15.7348
8 N4x N 24.0942 -13.6631
9 C8x C 24.3686 -11.1471
10 C8x C 22.2970 -9.9733
11 N1b N 19.4309 -16.4345
12 C5a C 21.8333 -16.4345
13 C8x C 23.6875 -9.9456
14 C5a C 18.2294 -15.7348
15 N1b N 23.0442 -15.7348
16 O5a O 21.8333 -17.8250
17 C1c C 17.0282 -16.4345
18 O5a O 18.2294 -14.3443
19 C1c C 24.2454 -16.4345
20 C1b C 17.0282 -17.8250
21 N1b N 15.8269 -15.7348
22 C5a C 25.4469 -15.7348
23 C1b C 24.2454 -17.8250
24 C8y C 18.2294 -18.5158
25 C5a C 14.6254 -16.4345
26 N1b N 26.6482 -16.4345
27 O5a O 25.4469 -14.3443
28 O1a O 25.4469 -18.5158
29 C8x C 19.5733 -18.1516
30 N5x N 18.1749 -19.9085
31 C1y C 13.4149 -15.7348
32 O5a O 14.6254 -17.8250
33 C1c C 27.8494 -15.7348
34 N4x N 20.3319 -19.3204
35 C8x C 19.4676 -20.4032
36 C1x C 12.0997 -16.1614
37 N1x N 13.4231 -14.3356
38 C1b C 27.8494 -14.3443
39 C5a C 29.0510 -16.4345
40 C1x C 11.2809 -15.0338
41 C5x C 12.0967 -13.9082
42 C8y C 29.0510 -13.6442
43 N1b N 30.2522 -15.7348
44 O5a O 29.0510 -17.8250
45 O5x O 11.6582 -12.5905
46 C8x C 30.2426 -14.3443
47 C8x C 29.0414 -12.2633
48 C1c C 31.4630 -16.4345
49 C8x C 31.4534 -13.6442
50 C8x C 30.2426 -11.5726
51 C5a C 32.6642 -15.7348
52 C1b C 31.4630 -17.8250
53 C8y C 31.4534 -12.2633
54 N1b N 33.8655 -16.4345
55 O5a O 32.6642 -14.3443
56 O2a O 30.2522 -18.5158
57 O1a O 32.6546 -11.5726
58 C1c C 35.0670 -15.7348
59 C1d C 30.2522 -19.8501
60 C5a C 36.2682 -16.4345
61 C1b C 35.0670 -14.3443
62 C1a C 30.2433 -21.3537
63 C1a C 31.6238 -19.8778
64 C1a C 28.9564 -19.8778
65 N1b N 37.4694 -15.7348
66 O5a O 36.2682 -17.8250
67 C1c C 36.2682 -13.6442
68 C1c C 38.6709 -16.4345
69 C1a C 36.2682 -12.2633
70 C1a C 37.4694 -14.3443
71 C5a C 39.8815 -15.7348
72 C1b C 38.6709 -17.8250
73 N1y N 41.0830 -16.4345
74 O5a O 39.8815 -14.3443
75 C1b C 37.4694 -18.5158
76 C1y C 42.4735 -16.4156
77 C1x C 40.6762 -17.7590
78 C1b C 37.4694 -19.8967
79 C1x C 42.9179 -17.7307
80 C5a C 43.6747 -15.7158
81 C1x C 41.8114 -18.5537
82 N1b N 36.2682 -20.5968
83 N1b N 44.8759 -16.4156
84 O5a O 43.6747 -14.3253
85 C2c C 35.0670 -19.8967
86 N1b N 44.8482 -19.1778
87 N1a N 33.8655 -20.5968
88 N2a N 35.0670 -18.5158
89 C5a C 43.6936 -19.8685
90 N1a N 43.6936 -21.2494
91 O5a O 42.6625 -19.3292
92 C6a C 43.5874 -12.9125
93 O6a O 44.8006 -13.6129
94 C1a C 42.3743 -13.6129
95 O6a O 43.5874 -11.5117
BOND 99
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 6 10 2
10 7 11 1
11 7 12 1
12 9 13 2
13 11 14 1
14 12 15 1
15 12 16 2
16 14 17 1
17 14 18 2
18 15 19 1
19 17 20 1
20 17 21 1
21 19 22 1
22 19 23 1
23 20 24 1
24 21 25 1
25 22 26 1
26 22 27 2
27 23 28 1
28 24 29 2
29 24 30 1
30 25 31 1
31 25 32 2
32 26 33 1
33 29 34 1
34 30 35 2
35 31 36 1
36 31 37 1
37 33 38 1
38 33 39 1
39 36 40 1
40 37 41 1
41 38 42 1
42 39 43 1
43 39 44 2
44 41 45 2
45 42 46 2
46 42 47 1
47 43 48 1
48 46 49 1
49 47 50 2
50 48 51 1
51 48 52 1
52 49 53 2
53 51 54 1
54 51 55 2
55 52 56 1
56 53 57 1
57 54 58 1
58 56 59 1
59 58 60 1
60 58 61 1
61 59 62 1
62 59 63 1
63 59 64 1
64 60 65 1
65 60 66 2
66 61 67 1
67 65 68 1
68 67 69 1
69 67 70 1
70 68 71 1
71 68 72 1
72 71 73 1
73 71 74 2
74 72 75 1
75 73 76 1
76 73 77 1
77 75 78 1
78 76 79 1
79 76 80 1
80 77 81 1
81 78 82 1
82 80 83 1
83 80 84 2
84 82 85 1
85 83 86 1
86 85 87 1
87 85 88 2
88 86 89 1
89 89 90 1
90 89 91 2
91 5 8 1
92 10 13 1
93 34 35 1
94 40 41 1
95 50 53 1
96 79 81 1
97 92 93 1
98 92 94 1
99 92 95 2
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