KEGG   DRUG: SparfloxacinHelp
Entry
D00590                      Drug                                   

Name
Sparfloxacin (JAN/USAN/INN);
SPFX;
Zagam (TN)
Formula
C19H22F2N4O3
Exact mass
392.166
Mol weight
392.3998
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: 
ATC code: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Structure map
Quinolones
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA09 Sparfloxacin
      D00590  Sparfloxacin (JAN/USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Sparfloxacin
      D00590  Sparfloxacin (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
110871-86-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8y C    26.0849  -16.6263
            2   C8y C    26.1375  -15.2275
            3   N4y N    27.3731  -17.3141
            4   C8y C    24.9428  -17.3375
            5   C8y C    27.3440  -14.5222
            6   C8y C    24.9312  -14.5339
            7   C1y C    27.3614  -18.7246
            8   C8x C    28.5739  -16.6030
            9   C8y C    23.7246  -16.6437
            10  X   F    24.9312  -18.7420
            11  C8y C    28.5622  -15.2042
            12  O5x O    27.3790  -13.1236
            13  C8y C    23.7189  -15.2392
            14  N1a N    24.9138  -13.1353
            15  C1x C    28.0492  -19.9427
            16  C1x C    26.6447  -19.9251
            17  C6a C    29.7626  -14.5107
            18  X   F    22.5008  -14.5456
            19  O6a O    30.9691  -15.2159
            20  O6a O    29.7509  -13.1120
            21  N1y N    22.5208  -17.3469
            22  C1x C    21.2917  -16.6454
            23  C1y C    20.0833  -17.3513
            24  N1x N    20.0904  -18.7507
            25  C1y C    21.3196  -19.4521
            26  C1x C    22.5279  -18.7462
            27  C1a C    21.3263  -20.8301
            28  C1a C    18.8612  -16.6540
BOND        31
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 2
            12    6  13 2
            13    6  14 1
            14    7  15 1
            15    7  16 1
            16   11  17 1
            17   13  18 1
            18   17  19 1
            19   17  20 2
            20    8  11 2
            21    9  13 1
            22   15  16 1
            23    9  21 1
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   21  26 1
            30   25  27 1 #Up
            31   23  28 1 #Up

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