KEGG   DRUG: D00597Help
Entry
D00597                      Drug                                   

Name
Acebutolol hydrochloride (JP16/USP);
Sectral (TN)
Product
  Generic
Formula
C18H28N2O4. HCl
Exact mass
372.1816
Mol weight
372.8869
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB04 Acebutolol
      D00597  Acebutolol hydrochloride (JP16/USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Acebutolol
    D00597  Acebutolol hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D00597  Acebutolol hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Acebutolol
      D00597  Acebutolol hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00597  Acebutolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
34381-68-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8y C    21.9841  -14.0731
            2   C8y C    20.7938  -14.7732
            3   C8x C    23.2443  -14.7732
            4   O2a O    21.9841  -12.6728
            5   C8x C    20.7938  -16.1735
            6   C5a C    19.5336  -14.0731
            7   C8x C    23.2443  -16.1035
            8   C1b C    23.1743  -11.9727
            9   C8y C    22.0541  -16.8737
            10  C1a C    18.3433  -14.7732
            11  O5a O    19.5336  -12.6728
            12  C1c C    24.3646  -12.6028
            13  N1b N    22.0541  -18.2740
            14  C1b C    25.6248  -11.9026
            15  O1a O    24.3646  -14.0031
            16  C5a C    20.8638  -18.9741
            17  N1b N    26.8151  -12.6028
            18  C1b C    19.6036  -18.2740
            19  O5a O    20.8638  -20.3744
            20  C1c C    28.0053  -11.9026
            21  C1b C    18.4133  -19.0441
            22  C1a C    29.2656  -12.5328
            23  C1a C    28.0053  -10.5024
            24  C1a C    17.2231  -18.3440
            25  X   Cl   31.9262  -16.3136
BOND        24
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     6  10 1
            10    6  11 2
            11    8  12 1
            12    9  13 1
            13   12  14 1
            14   12  15 1
            15   13  16 1
            16   14  17 1
            17   16  18 1
            18   16  19 2
            19   17  20 1
            20   18  21 1
            21   20  22 1
            22   20  23 1
            23   21  24 1
            24    7   9 2

» Japanese version   » Back

DBGET integrated database retrieval system