KEGG   DRUG: D00599Help
Entry
D00599                      Drug                                   

Name
Carteolol hydrochloride (JP16/USP);
Cartrol (TN);
Ocupress (TN)
Product
  Generic
Formula
C16H24N2O3. HCl
Exact mass
328.1554
Mol weight
328.8343
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor] [DS:H00612]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04970  Salivary secretion  
 
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA15 Carteolol
      D00599  Carteolol hydrochloride (JP16/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01ED Beta blocking agents
     S01ED05 Carteolol
      D00599  Carteolol hydrochloride (JP16/USP)
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Carteolol
    D00599  Carteolol hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00599  Carteolol hydrochloride (JP16/USP)
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D00599  Carteolol hydrochloride (JP16/USP)
   214  Antihypertensives
    2149  Others
     D00599  Carteolol hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Carteolol
      D00599  Carteolol hydrochloride (JP16/USP)
    beta2-adrenergic receptor
     Carteolol
      D00599  Carteolol hydrochloride (JP16/USP)
    beta3-adrenergic receptor
     Carteolol
      D00599  Carteolol hydrochloride (JP16/USP)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Carteolol
    D00599  Carteolol hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00599  Carteolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
51781-21-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   X   Cl   34.1717  -16.9041
            2   C1x C    24.1844  -15.2181
            3   C5x C    24.1844  -16.6229
            4   N1x N    25.4010  -17.3254
            5   C8y C    26.6177  -16.6229
            6   C8y C    26.6177  -15.2181
            7   C1x C    25.4010  -14.5157
            8   C8x C    27.8343  -17.3254
            9   C8x C    29.0509  -16.6229
            10  C8x C    29.0509  -15.2181
            11  C8y C    27.8343  -14.5157
            12  O5x O    22.9678  -17.3254
            13  O2a O    27.8343  -13.1108
            14  C1b C    29.0530  -12.4072
            15  C1c C    30.2536  -13.1006
            16  C1b C    31.4445  -12.4130
            17  O1a O    30.2537  -14.5154
            18  N1b N    32.6401  -13.1036
            19  C1d C    33.8337  -12.4145
            20  C1a C    35.0333  -11.7219
            21  C1a C    34.5265  -13.6153
            22  C1a C    33.1223  -11.1820
BOND        22
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     5   8 2
            8     8   9 1
            9     9  10 2
            10   10  11 1
            11    6  11 2
            12    3  12 2
            13   11  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   15  17 1
            18   16  18 1
            19   18  19 1
            20   19  20 1
            21   19  21 1
            22   19  22 1

» Japanese version   » Back

DBGET integrated database retrieval system