KEGG   DRUG: D00605Help
Entry
D00605                      Drug                                   

Name
Guanabenz acetate (JP16/USP);
Wytensin (TN)
Formula
C8H8Cl2N4. C2H4O2
Exact mass
290.0337
Mol weight
291.1339
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
Drug group: 
Target
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D00605  Guanabenz acetate (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha2-adrenergic receptor
     Guanabenz
      D00605  Guanabenz acetate (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00605  Guanabenz acetate
BRITE hierarchy
Other DBs
CAS: 
23256-50-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8y C    35.6331  -15.6265
            2   C8y C    35.6273  -17.0132
            3   C8y C    36.8385  -14.9186
            4   C2b C    34.4221  -14.9243
            5   C8x C    36.8385  -17.7154
            6   X   Cl   34.4162  -17.7154
            7   C8x C    38.0497  -15.6207
            8   X   Cl   36.8326  -13.5144
            9   N2b N    33.2109  -15.6265
            10  C8x C    38.0497  -17.0132
            11  N1b N    31.9998  -14.9243
            12  C2c C    30.7828  -15.6265
            13  N2a N    30.7828  -17.0250
            14  N1a N    29.5716  -14.9243
            15  C6a C    25.7100  -15.9541
            16  C1a C    24.4988  -16.6622
            17  O6a O    25.7041  -14.5498
            18  O6a O    26.9270  -16.6622
BOND        17
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    9  11 1
            11   11  12 1
            12   12  13 2
            13   12  14 1
            14    7  10 2
            15   15  16 1
            16   15  17 2
            17   15  18 1

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