KEGG   DRUG: D00633Help
Entry
D00633                      Drug                                   

Name
Dopamine hydrochloride (JP16/USP);
Actopamin (TN);
Intropin (TN)
Product
  Generic
Formula
C8H11NO2. HCl
Exact mass
189.0557
Mol weight
189.6394
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Adrenergic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
dopamine D1 receptor agonist [HSA:1812] [KO:K04144];
dopamine D2 receptor agonist [HSA:1813] [KO:K04145];
dopamine D3 receptor agonist [HSA:1814] [KO:K04146];
dopamine D4 receptor agonist [HSA:1815] [KO:K04147];
dopamine D5 receptor agonist [HSA:1816] [KO:K05840]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Metabolism
Enzyme: MAOB [HSA:4129], COMT [HSA:1312]
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA04 Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D00633  Dopamine hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor
     Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
    dopamine D2-receptor
     Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
    dopamine D3-receptor
     Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
    dopamine D4-receptor
     Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
    dopamine D5-receptor
     Dopamine
      D00633  Dopamine hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00633  Dopamine hydrochloride
  D00633  Dopamine hydrochloride injection
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from tyrosine
   Isoquinoline alkaloids
    D00633  Dopamine hydrochloride (JP15/USP)
BRITE hierarchy
Other DBs
CAS: 
62-31-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        12
            1   C8y C    28.7000  -14.7000
            2   C8x C    27.5100  -14.0000
            3   C8x C    28.7000  -16.1000
            4   C1b C    29.8900  -14.0000
            5   C8y C    26.3200  -14.7000
            6   C8x C    27.5100  -16.8000
            7   C1b C    31.1500  -14.7000
            8   C8y C    26.3200  -16.1000
            9   O1a O    25.0600  -14.0000
            10  N1a N    32.3400  -14.0000
            11  O1a O    25.0600  -16.8000
            12  X   Cl   32.5500  -16.8000
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    6   8 2

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