| Entry |
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| Name |
Bisoprolol fumarate (JP16/USP);
Zebeta (TN)
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| Product |
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| Generic |
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| Formula |
(C18H31NO4)2. C4H4O4
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| Exact mass |
766.4616
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| Mol weight |
766.9582
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| Structure |
     |
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| Activity |
Antihypertensive [beta-blocker]
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| Remark |
Therapeutic category: ATC code: |
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| Target |
beta1-adrenergic receptor antagonist [HSA: 153] [KO: K04141] |
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| Pathway |
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| Interaction |
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| Structure map |
| beta-Adrenergic receptor agonists/antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
212 Antiarrhythmic agents
2123 Beta blockers
D00634 Bisoprolol fumarate (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AB Beta blocking agents, selective
C07AB07 Bisoprolol
D00634 Bisoprolol fumarate (JP16/USP)
USP drug classification [BR:br08302]
Cardiovascular Agents
Beta-adrenergic Blocking Agents
Bisoprolol
D00634 Bisoprolol fumarate (JP16/USP)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
beta1-adrenergic receptor [HSA:153] [KO:K04141]
Bisoprolol [ATC:C07AB07]
D00634 Bisoprolol fumarate (JP16/USP)
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| Other DBs |
CAS: 104344-23-2 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 54
1 C2b C 24.3463 -9.3353
2 C2b C 25.5331 -8.6372
3 C6a C 23.1595 -8.7070
4 C6a C 26.7896 -9.3353
5 O6a O 21.9030 -9.4051
6 O6a O 23.1595 -7.2410
7 O6a O 27.9764 -8.6372
8 O6a O 26.7896 -10.7315
9 C8y C 11.2700 -7.3500
10 C8x C 12.5300 -8.0500
11 C8x C 10.0800 -8.0500
12 O2a O 11.2700 -5.9500
13 C8x C 12.5300 -9.4500
14 C8x C 10.0800 -9.4500
15 C1b C 12.5300 -5.3200
16 C8y C 11.2700 -10.1500
17 C1c C 13.7200 -5.9500
18 C1b C 11.2700 -11.5500
19 C1b C 14.9100 -5.3200
20 O1a O 13.7200 -7.3500
21 O2a O 10.0800 -12.2500
22 N1b N 16.1700 -5.9500
23 C1b C 8.8900 -11.5500
24 C1c C 17.3600 -5.3200
25 C1b C 7.7000 -12.2500
26 C1a C 18.5500 -5.9500
27 C1a C 17.3600 -3.9200
28 O2a O 6.5100 -11.5500
29 C1c C 5.3200 -12.2500
30 C1a C 4.0600 -11.5500
31 C1a C 5.3200 -13.6500
32 C8y C 11.2700 -7.3500
33 C8x C 12.5300 -8.0500
34 C8x C 12.5300 -9.4500
35 C8y C 11.2700 -10.1500
36 C1b C 11.2700 -11.5500
37 O2a O 10.0800 -12.2500
38 C1b C 8.8900 -11.5500
39 C1b C 7.7000 -12.2500
40 O2a O 6.5100 -11.5500
41 C1c C 5.3200 -12.2500
42 C1a C 4.0600 -11.5500
43 C1a C 5.3200 -13.6500
44 C8x C 10.0800 -9.4500
45 C8x C 10.0800 -8.0500
46 O2a O 11.2700 -5.9500
47 C1b C 12.5300 -5.3200
48 C1c C 13.7200 -5.9500
49 C1b C 14.9100 -5.3200
50 N1b N 16.1700 -5.9500
51 C1c C 17.3600 -5.3200
52 C1a C 18.5500 -5.9500
53 C1a C 17.3600 -3.9200
54 O1a O 13.7200 -7.3500
BOND 53
1 1 2 2
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 2
6 4 7 1
7 4 8 2
8 9 10 1
9 9 11 2
10 9 12 1
11 10 13 2
12 11 14 1
13 12 15 1
14 13 16 1
15 15 17 1
16 16 18 1
17 17 19 1
18 17 20 1
19 18 21 1
20 19 22 1
21 21 23 1
22 22 24 1
23 23 25 1
24 24 26 1
25 24 27 1
26 25 28 1
27 28 29 1
28 29 30 1
29 29 31 1
30 14 16 2
31 32 33 1
32 32 45 2
33 32 46 1
34 33 34 2
35 45 44 1
36 46 47 1
37 34 35 1
38 47 48 1
39 35 36 1
40 48 49 1
41 48 54 1
42 36 37 1
43 49 50 1
44 37 38 1
45 50 51 1
46 38 39 1
47 51 52 1
48 51 53 1
49 39 40 1
50 40 41 1
51 41 42 1
52 41 43 1
53 44 35 2
BRACKET 1 2.5900 -14.3500 2.5900 -3.3600
1 19.8800 -3.3600 19.8800 -14.3500
1 2
ORIGINAL 1 9 10 13 16 18 21 23 25 28 29 30 31 14 11 12 15
1 17 19 22 24 26 27 20
REPEAT 1 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47
1 48 49 50 51 52 53 54
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