KEGG   DRUG: D00650Help
Entry
D00650                      Drug                                   

Name
Bendroflumethiazide (JAN/USP/INN);
Naturetin (TN)
Formula
C15H14F3N3O4S2
Exact mass
421.0378
Mol weight
421.4146
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic;
Antihypertensive
Remark
Same as: 
ATC code: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03A LOW-CEILING DIURETICS, THIAZIDES
    C03AA Thiazides, plain
     C03AA01 Bendroflumethiazide
      D00650  Bendroflumethiazide (JAN/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Thiazide
   Bendroflumethiazide
    D00650  Bendroflumethiazide (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3 [HSA:6559] [KO:K14426] [TC:2.A.30.4.2]
     Bendroflumethiazide [ATC:C03AA01]
      D00650  Bendroflumethiazide (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
73-48-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C8y C    22.4579  -17.7208
            2   C8y C    22.4519  -16.3225
            3   C8x C    23.6639  -18.4257
            4   N1x N    21.2459  -18.4316
            5   C8x C    23.6639  -15.6234
            6   S2x S    21.2343  -15.6293
            7   C8y C    24.8815  -17.7208
            8   C1y C    20.0283  -17.7325
            9   C8y C    24.8815  -16.3225
            10  N1x N    20.0225  -16.3342
            11  O3c O    20.0283  -14.9126
            12  O3c O    22.4462  -14.9126
            13  C1d C    25.8720  -18.7170
            14  C1b C    18.8282  -18.4316
            15  S4a S    26.0876  -15.6234
            16  X   F    25.5107  -20.0686
            17  X   F    27.2294  -18.3500
            18  X   F    26.8741  -19.7076
            19  C8y C    17.6164  -17.7265
            20  N1a N    27.2877  -14.9185
            21  O3c O    27.1478  -16.5264
            22  O3c O    25.0912  -14.6272
            23  C8x C    16.4104  -18.4316
            24  C8x C    17.6105  -16.3284
            25  C8x C    15.1985  -17.7325
            26  C8x C    16.4104  -15.6350
            27  C8x C    15.1985  -16.3342
BOND        29
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 2
            9     6  10 1
            10    6  11 2
            11    6  12 2
            12    7  13 1
            13    8  14 1
            14    9  15 1
            15   13  16 1
            16   13  17 1
            17   13  18 1
            18   14  19 1
            19   15  20 1
            20   15  21 2
            21   15  22 2
            22   19  23 2
            23   19  24 1
            24   23  25 1
            25   24  26 2
            26   25  27 2
            27    7   9 1
            28    8  10 1
            29   26  27 1

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