KEGG   DRUG: D00651Help
Entry
D00651                      Drug                                   

Name
Benzthiazide (JAN/INN);
Exna (TN)
Formula
C15H14ClN3O4S3
Exact mass
430.9835
Mol weight
431.9374
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic;
Antihypertensive
Remark
Same as: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Brite
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3 [HSA:6559] [KO:K14426] [TC:2.A.30.4.2]
     Benzthiazide
      D00651  Benzthiazide (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
91-33-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8y C    23.6363  -18.5557
            2   C8y C    23.6304  -17.1500
            3   N5x N    22.4291  -19.2555
            4   C8x C    24.8376  -19.2496
            5   C8x C    24.8376  -16.4444
            6   S2x S    22.4174  -16.4504
            7   C8y C    21.2102  -18.5673
            8   C8y C    26.0565  -18.5557
            9   C8y C    26.0565  -17.1500
            10  N4x N    21.2043  -17.1617
            11  O3c O    23.6363  -15.7505
            12  O3c O    21.2102  -15.7446
            13  C1b C    20.0030  -19.2613
            14  X   Cl   27.2754  -19.2438
            15  S4a S    27.2695  -16.4561
            16  S2a S    18.7957  -18.5614
            17  N1a N    28.4710  -15.7505
            18  O3c O    28.2493  -17.4418
            19  O3c O    26.2723  -15.4588
            20  C1b C    17.5826  -19.2613
            21  C8y C    16.3696  -18.5614
            22  C8x C    15.1566  -19.2613
            23  C8x C    16.3696  -17.1617
            24  C8x C    13.9435  -18.5614
            25  C8x C    15.1566  -16.4619
            26  C8x C    13.9435  -17.1617
BOND        28
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     5   9 2
            9     6  10 1
            10    6  11 2
            11    6  12 2
            12    7  13 1
            13    8  14 1
            14    9  15 1
            15   13  16 1
            16   15  17 1
            17   15  18 2
            18   15  19 2
            19   16  20 1
            20   20  21 1
            21   21  22 1
            22   21  23 2
            23   22  24 2
            24   23  25 1
            25   24  26 1
            26    7  10 1
            27    8   9 1
            28   25  26 2

» Japanese version   » Back

DBGET integrated database retrieval system