KEGG   DRUG: D00654Help
Entry
D00654                      Drug                                   

Name
Hydroflumethiazide (JAN/USP/INN);
Saluron (TN)
Formula
C8H8F3N3O4S2
Exact mass
330.9908
Mol weight
331.292
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive;
Diuretic
Remark
Same as: 
ATC code: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03A LOW-CEILING DIURETICS, THIAZIDES
    C03AA Thiazides, plain
     C03AA02 Hydroflumethiazide
      D00654  Hydroflumethiazide (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3
     Hydroflumethiazide
      D00654  Hydroflumethiazide (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
135-09-1
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8y C    22.4065  -16.5814
            2   C8y C    22.4123  -15.1825
            3   C8x C    23.6122  -17.2897
            4   N1x N    21.2006  -17.2838
            5   C8x C    23.6239  -14.4860
            6   S2x S    21.2006  -14.4801
            7   C8y C    24.8296  -16.5931
            8   C1x C    19.9832  -16.5814
            9   C8y C    24.8356  -15.1942
            10  N1x N    19.9832  -15.1825
            11  O3c O    20.1881  -13.4850
            12  O3c O    22.4065  -13.7777
            13  C1d C    26.0355  -17.2897
            14  S4a S    26.0413  -14.4801
            15  X   F    27.2354  -16.5814
            16  X   F    26.0238  -18.6886
            17  X   F    27.2354  -17.9921
            18  N1a N    27.2472  -13.7777
            19  O3c O    27.2472  -15.1825
            20  O3c O    25.0405  -13.4850
BOND        21
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 2
            9     6  10 1
            10    6  11 2
            11    6  12 2
            12    7  13 1
            13    9  14 1
            14   13  15 1
            15   13  16 1
            16   13  17 1
            17   14  18 1
            18   14  19 2
            19   14  20 2
            20    7   9 1
            21    8  10 1

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