| Entry |
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| Name |
Methazolamide (JAN/USP/INN);
Neptazane (TN)
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| Product |
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| Generic |
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| Formula |
C5H8N4O3S2
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| Exact mass |
236.0038
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| Mol weight |
236.272
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| Structure |
     |
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| Activity |
Carbonic anhydrase inhibitor
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| Remark |
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| Target |
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| Pathway |
hsa04964 Proximal tubule bicarbonate reclamation | |
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| Interaction |
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| Structure map |
| Sulfonamide derivatives - diuretics | | Antiglaucoma agents |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC05 Methazolamide
D00655 Methazolamide (JAN/USP/INN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Carbonic Anhydrase Inhibitors
Methazolamide
D00655 Methazolamide (JAN/USP/INN)
Ophthalmic Agents
Ophthalmic Antiglaucoma Agents
Carbonic Anhydrase Inhibitors, Ophthalmic
Methazolamide
D00655 Methazolamide (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases
carbonic anhydrase [HSA:759 760 761 762 763 11238 765 766 767 768 771 377677 23632 100996556] [KO:K01672]
Methazolamide [ATC:S01EC05]
D00655 Methazolamide (JAN/USP/INN)
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| Other DBs |
CAS: 554-57-4 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 14
1 C8y C 26.4566 -18.5315
2 S2x S 25.3215 -17.7066
3 N4y N 26.0236 -19.8597
4 N2b N 27.6618 -17.8177
5 C8y C 24.1866 -18.5315
6 N5x N 24.6254 -19.8597
7 C1a C 26.8486 -20.9889
8 C5a C 28.8729 -18.5198
9 S4a S 22.7882 -18.5258
10 C1a C 30.0841 -17.8120
11 O5a O 28.8729 -19.9183
12 N1a N 22.8465 -19.9240
13 O3c O 22.8465 -17.1273
14 O3c O 21.3840 -18.5258
BOND 14
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 3 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 8 10 1
10 8 11 2
11 9 12 1
12 9 13 2
13 9 14 2
14 5 6 2
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