KEGG   DRUG: D00655Help
Entry
D00655                      Drug                                   

Name
Methazolamide (JAN/USP/INN);
Neptazane (TN)
Product
  Generic
Formula
C5H8N4O3S2
Exact mass
236.0038
Mol weight
236.272
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Carbonic anhydrase inhibitor
Remark
Same as: 
ATC code: 
Target
carbonic anhydrase inhibitor [HSA:759 760 761 762 763 11238 765 766 767 768 771 377677 23632] [KO:K01672 K18245 K18246]
  Pathway
hsa04964  Proximal tubule bicarbonate reclamation  
 
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EC Carbonic anhydrase inhibitors
     S01EC05 Methazolamide
      D00655  Methazolamide (JAN/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Carbonic Anhydrase Inhibitors
   Methazolamide
    D00655  Methazolamide (JAN/USP/INN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Methazolamide
    D00655  Methazolamide (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases
   carbonic anhydrase
    Methazolamide
     D00655  Methazolamide (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
554-57-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8y C    26.4566  -18.5315
            2   S2x S    25.3215  -17.7066
            3   N4y N    26.0236  -19.8597
            4   N2b N    27.6618  -17.8177
            5   C8y C    24.1866  -18.5315
            6   N5x N    24.6254  -19.8597
            7   C1a C    26.8486  -20.9889
            8   C5a C    28.8729  -18.5198
            9   S4a S    22.7882  -18.5258
            10  C1a C    30.0841  -17.8120
            11  O5a O    28.8729  -19.9183
            12  N1a N    22.8465  -19.9240
            13  O3c O    22.8465  -17.1273
            14  O3c O    21.3840  -18.5258
BOND        14
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     8  10 1
            10    8  11 2
            11    9  12 1
            12    9  13 2
            13    9  14 2
            14    5   6 2

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