KEGG   DRUG: D00662Help
Entry
D00662                      Drug                                   

Name
Azatadine maleate (USP);
Optimine (TN)
Formula
C20H22N2. (C4H4O4)2
Exact mass
522.2002
Mol weight
522.5464
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihistaminic
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX09 Azatadine
      D00662  Azatadine maleate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Azatadine
      D00662  Azatadine maleate (USP)
BRITE hierarchy
Other DBs
CAS: 
3978-86-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        38
            1   C2b C    31.8925  -14.7352
            2   C2b C    30.3466  -14.7412
            3   C6a C    32.5380  -15.8488
            4   C6a C    29.7070  -15.8606
            5   O6a O    31.8983  -16.9681
            6   O6a O    33.8293  -15.8428
            7   O6a O    28.4156  -15.8606
            8   O6a O    30.3585  -16.9741
            9   C1x C    21.3324  -20.1510
            10  C8y C    20.4913  -19.0427
            11  C8y C    20.8261  -17.6875
            12  C2y C    22.0857  -17.1101
            13  C1x C    22.7366  -20.1762
            14  C8y C    23.3378  -17.7317
            15  C8y C    23.6240  -19.0988
            16  C8x C    19.8202  -16.7203
            17  C8x C    18.4798  -17.1079
            18  C8x C    18.1450  -18.4631
            19  C8x C    19.1509  -19.4301
            20  C8x C    24.9536  -19.5354
            21  C8x C    25.9966  -18.6021
            22  C8x C    25.7105  -17.2350
            23  N5x N    24.3807  -16.7984
            24  C2y C    22.1071  -15.6769
            25  C1x C    23.3195  -14.9769
            26  C1x C    23.3195  -13.5769
            27  N1y N    22.1071  -12.8769
            28  C1x C    20.8946  -13.5769
            29  C1x C    20.8946  -14.9769
            30  C1a C    22.1071  -11.4801
            31  C2b C    31.8925  -14.7352
            32  C2b C    30.3466  -14.7412
            33  C6a C    29.7070  -15.8606
            34  O6a O    28.4156  -15.8606
            35  O6a O    30.3585  -16.9741
            36  C6a C    32.5380  -15.8488
            37  O6a O    31.8983  -16.9681
            38  O6a O    33.8293  -15.8428
BOND        39
            1    11  12 1
            2     9  13 1
            3    12  14 1
            4    10  11 1
            5    13  15 1
            6     9  10 1
            7    14  15 1
            8    11  16 2
            9    16  17 1
            10   17  18 2
            11   18  19 1
            12   10  19 2
            13   15  20 2
            14   20  21 1
            15   21  22 2
            16   22  23 1
            17   14  23 2
            18   12  24 2
            19   24  25 1
            20   25  26 1
            21   26  27 1
            22   27  28 1
            23   28  29 1
            24   24  29 1
            25   27  30 1
            26    1   2 2
            27    1   3 1
            28    2   4 1
            29    3   5 1
            30    3   6 2
            31    4   7 1
            32    4   8 2
            33   31  32 2
            34   31  36 1
            35   32  33 1
            36   36  37 1
            37   36  38 2
            38   33  34 1
            39   33  35 2
BRACKET     1    27.0900  -17.9900   27.0900  -14.0000
            1    34.4400  -14.0000   34.4400  -17.9900
            1  2
 ORIGINAL  1    1   2   4   7   8   3   5   6
 REPEAT    1   31  32  33  34  35  36  37  38

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