| Entry |
|
|---|
| Name |
Pirbuterol acetate (USAN);
Maxair (TN) |
|---|
| Formula |
C12H20N2O3. C2H4O2
|
|---|
| Exact mass |
300.1685
|
|---|
| Mol weight |
300.3508
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AC Selective beta-2-adrenoreceptor agonists
R03AC08 Pirbuterol
D00686 Pirbuterol acetate (USAN)
R03C ADRENERGICS FOR SYSTEMIC USE
R03CC Selective beta-2-adrenoreceptor agonists
R03CC07 Pirbuterol
D00686 Pirbuterol acetate (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01048 Pirbuterol
D00686 Pirbuterol acetate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D00686 Pirbuterol acetate (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01048 Pirbuterol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C6a C 23.6413 -18.2117
2 C1a C 22.4365 -18.9160
3 O6a O 24.8521 -18.9160
4 O6a O 23.6356 -16.8150
5 C8y C 13.0200 -18.0600
6 N5x N 11.7600 -18.7600
7 C1c C 14.2100 -18.7600
8 C8x C 13.0200 -16.6600
9 C8y C 10.5700 -18.0600
10 C1b C 15.4000 -18.0600
11 O1a O 14.2100 -20.1600
12 C8x C 11.7600 -15.9600
13 C8y C 10.5700 -16.6600
14 C1b C 9.3800 -18.7600
15 N1b N 16.5900 -18.7600
16 O1a O 9.3800 -15.9600
17 O1a O 8.0500 -18.0600
18 C1d C 17.8500 -18.0600
19 C1a C 19.0400 -17.3600
20 C1a C 18.5500 -19.2500
21 C1a C 17.1500 -16.8700
BOND 20
1 1 2 1
2 1 3 1
3 1 4 2
4 5 6 1
5 5 7 1
6 5 8 2
7 6 9 2
8 7 10 1
9 7 11 1
10 8 12 1
11 9 13 1
12 9 14 1
13 10 15 1
14 13 16 1
15 14 17 1
16 15 18 1
17 12 13 2
18 18 19 1
19 18 20 1
20 18 21 1
|
|---|
