KEGG   DRUG: Thiamylal sodiumHelp
Entry
D00713                      Drug                                   

Name
Thiamylal sodium (JP17);
Surital (TN)
Formula
C12H17N2O2S. Na
Exact mass
276.0908
Mol weight
276.3303
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01837  Barbiturate sedative-hypnotics
 DG01567  GABA-A receptor agonist
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02025  Barbiturate anesthetics
 DG02027  General anesthetics
  DG02025  Barbiturate anesthetics
 DG02025  Barbiturate anesthetics
Remark
Therapeutic category: 1115
Chemical structure group: DG01377
Product (DG01377): D00713<JP>
Efficacy
Anesthetic (intravenous)
Comment
Barbiturates
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Drug interaction
Structure map
map07230  GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   111  General anesthetics
    1115  Barbiturates and thiobarbiturates
     D00713  Thiamylal sodium (JP17)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00713  Thiamylal sodium (JP17) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00713  Thiamylal sodium
  D00713  Thiamylal sodium for injection
Drug classes of therapeutic agents [br08360.html]
 Psychiatric agents
  D00713
 Anesthetics, analgesics and anti-inflammatory drugs
  D00713
BRITE hierarchy
Other DBs
CAS: 337-47-3
PubChem: 7847778
ChEBI: 9537
ChEMBL: CHEMBL1201065
LigandBox: D00713
NIKKAJI: J399.152K
KCF data Show

ATOM        18
            1   C1z C    26.1276  -18.6319
            2   C5x C    26.1276  -20.0395
            3   C5x C    24.9186  -17.9370
            4   C1c C    27.5235  -18.6319
            5   C1b C    26.1218  -17.2361
            6   N1x N    24.9186  -20.7461
            7   O5x O    27.3308  -20.7461
            8   N2x N    23.6980  -18.6319
            9   O5x O    24.9012  -16.5295
            10  C1b C    28.2127  -17.4172
            11  C1a C    28.4987  -19.6306
            12  C2b C    27.3308  -16.5353
            13  C2y C    23.6980  -20.0395
            14  C1b C    29.6084  -17.4172
            15  C2a C    27.3308  -15.1395
            16  S1a S    22.4775  -20.7344 #-
            17  C1a C    30.3034  -16.2082
            18  Z   Na   20.0940  -20.8783 #+
BOND        17
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 2
            7     3   8 1
            8     3   9 2
            9     4  10 1
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13   10  14 1
            14   12  15 2
            15   13  16 1
            16   14  17 1
            17    8  13 2

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