KEGG   DRUG: D00720Help
Entry
D00720                      Drug                                   

Name
Mepenzolate bromide (JP16/INN);
Cantil (TN)
Product
Formula
C21H26NO3. Br
Exact mass
419.1096
Mol weight
420.34
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
Therapeutic category: 
ATC code: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   123  Autonomic nervous system agents
    1231  Quaternary ammoniums
     D00720  Mepenzolate bromide (JP16/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AB Synthetic anticholinergics, quaternary ammonium compounds
     A03AB12 Mepenzolate
      D00720  Mepenzolate bromide (JP16/INN)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Mepenzolate
    D00720  Mepenzolate bromide (JP16/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Mepenzolate [ATC:A03AB12]
      D00720  Mepenzolate bromide (JP16/INN)
BRITE hierarchy
Other DBs
CAS: 
76-90-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   X   Br   20.3708  -17.3488 #-
            2   C1x C    22.4560  -15.3909
            3   C1x C    23.6669  -14.6918
            4   C1y C    24.8779  -15.3909
            5   O7a O    26.0887  -14.6918
            6   C7a C    27.2996  -15.3909
            7   C1d C    28.5106  -14.6918
            8   C8y C    29.7214  -15.3909
            9   C8x C    30.9323  -14.6918
            10  C8x C    29.7214  -16.7891
            11  C8x C    30.9323  -17.4882
            12  C8x C    32.1433  -16.7891
            13  C8x C    32.1433  -15.3909
            14  C8y C    28.5106  -13.2938
            15  C8x C    29.7422  -12.5824
            16  C8x C    29.7420  -11.1842
            17  C8x C    28.5309  -10.4853
            18  C8x C    27.2993  -11.1967
            19  C8x C    27.2995  -12.5949
            20  O6a O    27.2996  -16.7890
            21  C1x C    24.8779  -16.7889
            22  C1x C    22.4560  -16.7891
            23  N2y N    23.6669  -17.4882 #+
            24  C1a C    24.3660  -18.6991
            25  C1a C    22.9678  -18.6991
            26  O1a O    29.7214  -13.9927
BOND        27
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8     8  10 2
            9    10  11 1
            10   11  12 2
            11   12  13 1
            12    9  13 2
            13    7  14 1
            14   14  15 2
            15   15  16 1
            16   16  17 2
            17   17  18 1
            18   18  19 2
            19   14  19 1
            20    6  20 2
            21    4  21 1
            22    2  22 1
            23   22  23 1
            24   23  21 1
            25   23  24 1
            26   23  25 1
            27    7  26 1

» Japanese version   » Back

DBGET integrated database retrieval system