KEGG   DRUG: Interferon alfa-2aHelp
Entry
D00745                      Drug                                   

Name
Interferon alfa-2a (USAN/INN);
Interferon alfa-2a (genetical recombination) (JAN);
Roferon A (TN)
Formula
C860H1353N227O255S9
Exact mass
19228.7369
Mol weight
19240.8977
Sequence
CDLPQTHSLG SRRTLMLLAQ MRKISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI
QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR
KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
  Type
Peptide
Class
Antineoplastic
 DG01752  Interferone
Remark
ATC code: 
Chemical group: 
Activity
Antineoplastic, Biological response modifier
Target
IFNAR1 [HSA:3454] [KO:K05130];
IFNAR2 [HSA:3455] [KO:K05131]
  Pathway
Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Hepatitis C
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB04 Interferon alfa-2a
      D00745  Interferon alfa-2a (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon receptor 1
    Interferon alfa-2a
     D00745  Interferon alfa-2a (USAN/INN)
   interferon receptor 2
    Interferon alfa-2a
     D00745  Interferon alfa-2a (USAN/INN)
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00745
BRITE hierarchy
Other DBs
CAS: 
76543-88-9
PubChem: 
ChEBI: 
DrugBank: 

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