KEGG   DRUG: Interferon beta-1bHelp
Entry
D00746                      Drug                                   

Name
Interferon beta-1b (USAN/INN);
Interferon beta-1b (genetical recombination) (JAN);
Betaseron (TN);
Extavia (TN)
Product
Formula
C903H1399N245O252S5
Exact mass
19867.2792
Mol weight
19879.5855
Sequence
SYNLLGFLQR SSNFQSQKLL WQLNGRLEYC LKDRMNFDIP EEIKQLQQFQ KEDAALTIYE
MLQNIFAIFR QDSSSTGWNE TIVENLLANV YHQINHLKTV LEEKLEKEDF TRGKLMSSLH
LKRYYGRILH YLKAKEYSHC AWTIVRVEIL RNFYFINRLT GYLRN
  Type
Peptide
Class
Antineoplastic
 DG01752  Interferone
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Immunomodulator
Target
interferon receptor 1 [HSA:3454] [KO:K05130];
interferon receptor 2 [HSA:3455] [KO:K05131]
  Pathway
Cytokine-cytokine receptor interaction
Osteoclast differentiation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB08 Interferon beta-1b
      D00746  Interferon beta-1b (USAN/INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Multiple Sclerosis Agents
   Interferon beta-1b
    D00746  Interferon beta-1b (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D00746  Interferon beta-1b (USAN/INN); Interferon beta-1b (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon receptor 1
    Interferon beta-1b
     D00746  Interferon beta-1b (USAN/INN)
   interferon receptor 2
    Interferon beta-1b
     D00746  Interferon beta-1b (USAN/INN)
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00746
BRITE hierarchy
Other DBs
CAS: 
145155-23-3
PubChem: 
DrugBank: 

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