KEGG   DRUG: D00746Help
Entry
D00746                      Drug                                   

Name
Interferon beta-1b (genetical recombination) (JAN);
Interferon beta-1b (USAN/INN);
Betaseron (TN);
Extavia (TN)
Product
Formula
C903H1399N245O252S5
Exact mass
19867.2792
Mol weight
19879.5855
Sequence
SYNLLGFLQR SSNFQSQKLL WQLNGRLEYC LKDRMNFDIP EEIKQLQQFQ KEDAALTIYE
MLQNIFAIFR QDSSSTGWNE TIVENLLANV YHQINHLKTV LEEKLEKEDF TRGKLMSSLH
LKRYYGRILH YLKAKEYSHC AWTIVRVEIL RNFYFINRLT GYLRN
  Type
Peptide
Activity
Immunomodulator
Remark
Therapeutic category: 
ATC code: 
Target
interferon receptor 1 agonist [HSA:3454] [KO:K05130];
interferon receptor 2 agonist [HSA:3455] [KO:K05131]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04380  Osteoclast differentiation
hsa04620  Toll-like receptor signaling pathway
hsa04630  Jak-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB08 Interferon beta-1b
      D00746  Interferon beta-1b (genetical recombination) (JAN); Interferon beta-1b (USAN/INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Multiple Sclerosis Agents
   Interferon beta-1b
    D00746  Interferon beta-1b (genetical recombination) (JAN); Interferon beta-1b (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D00746  Interferon beta-1b (genetical recombination) (JAN); Interferon beta-1b (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon receptor 1
    Interferon beta-1b
     D00746  Interferon beta-1b (genetical recombination) (JAN); Interferon beta-1b (USAN/INN)
   interferon receptor 2
    Interferon beta-1b
     D00746  Interferon beta-1b (genetical recombination) (JAN); Interferon beta-1b (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
145155-23-3
PubChem: 
DrugBank: 

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