KEGG   DRUG: D00747Help
Entry
D00747                      Drug                                   

Name
Interferon gamma-1b (USAN/INN);
Actimmune (TN)
Product
Formula
C734H1166N204O216S5
Exact mass
16454.513
Mol weight
16464.674
Sequence
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN
FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE
LSPAAKTGKR KRSQMLFRGR
  Type
Peptide
Activity
Antineoplastic;
Biological response modifier;
Immunoregulator
Remark
ATC code: 
Drug group: 
Target
interferon gamma receptor 1 agonist [HSA:3459] [KO:K05132];
interferon gamma receptor 2 agonist [HSA:3460] [KO:K05133]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB03 Interferon gamma
      D00747  Interferon gamma-1b (USAN/INN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immunomodulators
   Interferon gamma-1b, Recombinant
    D00747  Interferon gamma-1b (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon gamma receptor 1
    Interferon gamma
     D00747  Interferon gamma-1b (USAN/INN)
   interferon gamma receptor 2
    Interferon gamma
     D00747  Interferon gamma-1b (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
98059-61-1
PubChem: 
DrugBank: 

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