KEGG   DRUG: Interferon gamma-1bHelp
Entry
D00747                      Drug                                   

Name
Interferon gamma-1b (USAN/INN);
Actimmune (TN)
Product
Formula
C734H1166N204O216S5
Exact mass
16454.513
Mol weight
16464.674
Sequence
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN
FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE
LSPAAKTGKR KRSQMLFRGR
  Type
Peptide
Class
Antineoplastic
 DG01752  Interferone
Remark
ATC code: 
Chemical group: 
Activity
Antineoplastic, Immunomodulator, Biological response modifier
Target
IFNGR1 (CD119) [HSA:3459] [KO:K05132];
IFNGR2 [HSA:3460] [KO:K05133]
  Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB03 Interferon gamma
      D00747  Interferon gamma-1b (USAN/INN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immunomodulators
   Interferon gamma-1b, Recombinant
    D00747  Interferon gamma-1b (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon gamma receptor 1
    Interferon gamma
     D00747  Interferon gamma-1b (USAN/INN)
   interferon gamma receptor 2
    Interferon gamma
     D00747  Interferon gamma-1b (USAN/INN)
Antineoplastics [br08340.html]
 D00747
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00747
BRITE hierarchy
Other DBs
CAS: 
98059-61-1
PubChem: 
DrugBank: 

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