| Entry |
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| Name |
Aldesleukin (USAN/INN);
Interleukin-2;
Proleukin (TN)
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| Product |
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| Formula |
C690H1115N177O203S6
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| Exact mass |
15321.0691
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| Mol weight |
15330.6902
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| Sequence |
Pro Thr Ser Ser Ser Thr Lys Lys Thr Gln Leu Gln Leu Glu His Leu
Leu Leu Asp Leu Gln Met Ile Leu Asn Gly Ile Asn Asn Tyr Lys Asn
Pro Lys Leu Thr Arg Met Leu Thr Phe Lys Phe Tyr Met Pro Lys Lys
Ala Thr Glu Leu Lys His Leu Gln Cys Leu Glu Glu Glu Leu Lys Pro
Leu Glu Glu Val Leu Asn Leu Ala Gln Ser Lys Asn Phe His Leu Arg
Pro Arg Asp Leu Ile Ser Asn Ile Asn Val Ile Val Leu Glu Leu Lys
Gly Ser Glu Thr Thr Phe Met Cys Glu Tyr Ala Asp Glu Thr Ala Thr
Ile Val Glu Phe Leu Asn Arg Trp Ile Thr Phe Ser Gln Ser Ile Ile
Ser Thr Leu Thr |
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| Type |
Peptide |
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| Activity |
Antineoplastic;
Biological response modifier;
Immunostimulant
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| Remark |
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| Comment |
recombinant interleukin-2 [HSA: 3558] [KO: K05429]
Cytokine
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| Target |
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| Pathway |
hsa04060 Cytokine-cytokine receptor interaction
hsa04630 Jak-STAT signaling pathway | |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L03 IMMUNOSTIMULANTS
L03A IMMUNOSTIMULANTS
L03AC Interleukins
L03AC01 Aldesleukin
D00748 Aldesleukin (USAN/INN)
Target-based classification of drugs [BR:br08310]
Cytokine receptors
Class I cytokine receptors (hematopoietin family receptors)
interleukin 2 receptor [HSA:3559 3560 3561] [KO:K05068 K05069 K05070]
Aldesleukin
D00748 Aldesleukin (USAN/INN)
Antineoplastics [BR:br08308]
Biologic response modifiers
Interleukins
Aldesleukin [ATC:L03AC01]
D00748 Aldesleukin (USAN/INN)
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| Other DBs |
CAS: 110942-02-4 PubChem: DrugBank: |
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