KEGG   DRUG: D00779Help
Entry
D00779                      Drug                                   

Name
Biperiden (JAN/USP/INN);
Akineton (TN)
Formula
C21H29NO
Exact mass
311.2249
Mol weight
311.4611
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic;
Antiparkinsonian [DS:H00057]
Remark
Same as: 
ATC code: 
Comment
Centrally active anticholinergic drugs
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D00779  Biperiden (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Biperiden [ATC:N04AA02]
      D00779  Biperiden (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
514-65-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1y C    26.3034   -7.3312
            2   C1d C    26.3034   -8.7346
            3   C1y C    27.5665   -6.6295
            4   C1x C    25.1105   -6.6295
            5   C8y C    27.5665   -9.4363
            6   C1b C    25.1105   -9.4363
            7   C1x C    26.5841   -5.6471
            8   C2x C    27.5665   -5.2260
            9   C1y C    25.1105   -5.2260
            10  C8x C    27.5665  -10.8397
            11  C8x C    28.7594   -8.7346
            12  C1b C    23.9176   -8.7346
            13  C2x C    26.3736   -4.5243
            14  C8x C    28.6892  -11.5414
            15  C8x C    29.9523   -9.5065
            16  N1y N    22.6545   -9.4363
            17  C8x C    29.9523  -10.8397
            18  C1x C    22.6545  -10.8397
            19  C1x C    21.4616   -8.7346
            20  C1x C    21.4616  -11.4713
            21  C1x C    20.2687   -9.4363
            22  C1x C    20.2687  -10.7696
            23  O1a O    27.5188   -8.0329
BOND        26
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 1
            12    8  13 2
            13   10  14 2
            14   11  15 1
            15   12  16 1
            16   14  17 1
            17   16  18 1
            18   16  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22    7   9 1
            23    9  13 1
            24   15  17 2
            25   21  22 1
            26    2  23 1

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