KEGG   DRUG: D00822Help
Entry
D00822                      Drug                                   

Name
Citalopram hydrobromide (USAN);
Celexa (TN)
Product
  Generic
CITALOPRAM (American Health Packaging), CITALOPRAM (Amneal Pharmaceuticals), CITALOPRAM (Aphena Pharma Solutions - New Jersey), CITALOPRAM (Apotex Corp.), CITALOPRAM (Aurolife Pharma LLC), CITALOPRAM (Blenheim Pharmacal), CITALOPRAM (Blenheim Pharmacal), CITALOPRAM (Blenheim Pharmacal), CITALOPRAM (Blu Pharmaceuticals), CITALOPRAM (Camber Pharmaceuticals), CITALOPRAM (Cardinal Health), CITALOPRAM (Cardinal Health), CITALOPRAM (Clinical Solutions Wholesale), CITALOPRAM (Clinical Solutions Wholesale), PERRIGO CITALOPRAM (Contract Pharmacy Services-PA), CITALOPRAM (Contract Pharmacy Services-PA), CITALOPRAM (Epic Pharma), CITALOPRAM HYDROBROMIDE (Exelan Pharmaceuticals), CITALOPRAM (Golden State Medical Supply), CITALOPRAM (H.J. Harkins Company), CITALOPRAM HYDROBROMIDE (International Labs), CITALOPRAM (International Labs), CITALOPRAM (International Labs), CITALOPRAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CITALOPRAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CITALOPRAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CITALOPRAM (Lake Erie Medical DBA Quality Care Products LLC), CITALOPRAM (Legacy Pharmaceutical Packaging), CITALOPRAM (McKesson Contract Packaging), CITALOPRAM (MedVantx), CITALOPRAM (MedVantx), CITALOPRAM (MedVantx), CITALOPRAM (Mylan Pharmaceuticals), CITALOPRAM (NCS HealthCare of KY), CITALOPRAM (NCS HealthCare of KY), CITALOPRAM (New Horizon Rx Group), CITALOPRAM (PD-Rx Pharmaceuticals), CITALOPRAM (PD-Rx Pharmaceuticals), PERRIGO CITALOPRAM (Perrigo New York), PERRIGO CITALOPRAM (Perrigo New York), PERRIGO CITALOPRAM (Perrigo New York), CITALOPRAM (Preferred Pharmaceuticals), CITALOPRAM (REMEDYREPACK), CITALOPRAM (REMEDYREPACK), CITALOPRAM (REMEDYREPACK), CITALOPRAM (REMEDYREPACK), CITALOPRAM (REMEDYREPACK), CITALOPRAM (REMEDYREPACK), CITALOPRAM (Rebel Distributors Corp), CITALOPRAM (State of Florida DOH Central Pharmacy), CITALOPRAM (Teva Pharmaceuticals USA), CITALOPRAM (Unit Dose Services), CITALOPRAM HYDROBROMIDE (Aidarex Pharmaceuticals LLC), CITALOPRAM (Aurobindo Pharma Limited), CITALOPRAM HYDROBROMIDE (Aurobindo Pharma Limited), CITALOPRAM HYDROBROMIDE (Bryant Ranch Prepack), CITALOPRAM HYDROBROMIDE (Bryant Ranch Prepack), CITALOPRAM HYDROBROMIDE (Bryant Ranch Prepack), CITALOPRAM HYDROBROMIDE (Caraco Pharmaceutical Laboratories), CITALOPRAM HYDROBROMIDE (Cardinal Health), CITALOPRAM HYDROBROMIDE (Cardinal Health), CITALOPRAM HYDROBROMIDE (Clinical Solutions Wholesale), CITALOPRAM HYDROBROMIDE (Contract Pharmacy Services-PA), CITALOPRAM (Contract Pharmacy Services-PA), CITALOPRAM HYDROBROMIDE (Contract Pharmacy Services-PA), CITALOPRAM HYDROBROMIDE (Dr. Reddy's Laboratories Limited), CITALOPRAM HYDROBROMIDE (Glenmark Generics), CITALOPRAM (Greenstone LLC), CITALOPRAM HYDROBROMIDE (International Labs), CITALOPRAM HYDROBROMIDE (Legacy Pharmaceutical Packaging), CITALOPRAM (Legacy Pharmaceutical Packaging), CITALOPRAM HYDROBROMIDE (Major Pharmaceuticals), CITALOPRAM HYDROBROMIDE (MedVantx), CITALOPRAM HYDROBROMIDE (MedVantx), CITALOPRAM HYDROBROMIDE (MedVantx), CITALOPRAM HYDROBROMIDE (MedVantx), CITALOPRAM HYDROBROMIDE (MedVantx), CITALOPRAM HYDROBROMIDE (PD-Rx Pharmaceuticals), CITALOPRAM HYDROBROMIDE (PD-Rx Pharmaceuticals), CITALOPRAM HYDROBROMIDE (PD-Rx Pharmaceuticals), CITALOPRAM HYDROBROMIDE (PD-Rx Pharmaceuticals), CITALOPRAM (Physicians Total Care), CITALOPRAM HYDROBROMIDE (Preferred Pharmaceuticals), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (REMEDYREPACK), CITALOPRAM HYDROBROMIDE (Rebel Distributors Corp), CITALOPRAM (Rebel Distributors Corp.), CITALOPRAM (RedPharm Drug), CITALOPRAM HYDROBROMIDE (Roxane Laboratories), CITALOPRAM HYDROBROMIDE (Sandoz), CITALOPRAM HYDROBROMIDE (Silarx Pharmaceuticals), CITALOPRAM HYDROBROMIDE (St Marys Medical Park Pharmacy), CITALOPRAM HYDROBROMIDE (St Marys Medical Park Pharmacy), CITALOPRAM HYDROBROMIDE (Stat Rx USA), CITALOPRAM (State of Florida DOH Central Pharmacy), CITALOPRAM HYDROBROMIDE (State of Florida DOH Central Pharmacy), CITALOPRAM HYDROBROMIDE (State of Florida DOH Central Pharmacy), CITALOPRAM HYDROBROMIDE (Torrent Pharmaceuticals Limited), CITALOPRAM HYDROBROMIDE (Unit Dose Services)
Formula
C20H21FN2O. HBr
Exact mass
404.09
Mol weight
405.3039
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant [selective serotonin reuptake inhibitor]
Remark
ATC code: 
Comment
Selective serotonin reuptake inhibitor (SSRI)
Target
serotonin transporter inhibitor [HSA:6532] [KO:K05037]
  Pathway
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP2D6 [HSA:1565]
Transporter: ABCB1 [HSA:5243]
Interaction
Genomic biomarker: CYP2C19 [HSA:1557], CYP2D6 [HSA:1565]
CYP inhibition: CYP2C19 [HSA:1557]
Drug interaction
Structure map
Antidepressants
Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AB Selective serotonin reuptake inhibitors
     N06AB04 Citalopram
      D00822  Citalopram hydrobromide (USAN)
USP drug classification [BR:br08302]
 Antidepressants
  SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors)
   Citalopram
    D00822  Citalopram hydrobromide (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A4 (serotonin transporter) [HSA:6532] [KO:K05037]
     Citalopram [ATC:N06AB04]
      D00822  Citalopram hydrobromide (USAN)
BRITE hierarchy
Other DBs
CAS: 
59729-32-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1z C    25.2140  -17.1075
            2   C8y C    23.8790  -16.6700
            3   O2x O    26.0478  -15.9763
            4   C8y C    23.8847  -15.2650
            5   C8x C    22.6778  -17.3697
            6   C1x C    25.2257  -14.8335
            7   C8x C    22.6778  -14.5654
            8   C8x C    21.4593  -16.6643
            9   C8y C    21.4593  -15.2650
            10  C3b C    20.2466  -14.5654
            11  N3a N    19.0343  -13.8655
            12  C8y C    25.2140  -18.5075
            13  C8x C    24.0032  -19.2065
            14  C8x C    24.0032  -20.6065
            15  C8y C    25.2156  -21.3065
            16  C8x C    26.4264  -20.6075
            17  C8x C    26.4264  -19.2075
            18  X   F    25.2153  -22.6799
            19  C1b C    26.6140  -17.1075
            20  C1b C    27.2986  -18.2932
            21  C1b C    28.6998  -18.2932
            22  N1c N    29.3899  -19.4882
            23  C1a C    30.7997  -19.4882
            24  C1a C    28.7046  -20.6751
            25  X   Br   20.5107  -20.3997
BOND        26
            1     1   2 1
            2     1   3 1
            3     2   4 2
            4     2   5 1
            5     3   6 1
            6     4   7 1
            7     5   8 2
            8     7   9 2
            9     9  10 1
            10    4   6 1
            11    8   9 1
            12   10  11 3
            13    1  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20   15  18 1
            21    1  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   22  24 1

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