| Entry |
|
|---|
| Name |
Tranylcypromine sulfate (USP);
Parnate (TN) |
|---|
| Product |
|
|---|
| Generic |
|
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| Formula |
(C9H11N)2. H2SO4
|
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| Exact mass |
364.1457
|
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| Mol weight |
364.4592
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
|
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| Remark |
| Product (DG00949): | D00826<US> |
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase (MAO) inhibitor |
|---|
| Disease |
Major depressive disorder [DS: H01646] |
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| Target |
|
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| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00330 | Arginine and proline metabolism |
| hsa00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Interaction |
|
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| Structure map |
| map07216 | Catecholamine transferase inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AF Monoamine oxidase inhibitors, non-selective
N06AF04 Tranylcypromine
D00826 Tranylcypromine sulfate (USP) <US>
USP drug classification [BR:br08302]
Antidepressants
Monoamine Oxidase Inhibitors
Tranylcypromine
D00826 Tranylcypromine sulfate (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00949 Tranylcypromine
D00826 Tranylcypromine sulfate
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAO
D00826 Tranylcypromine sulfate (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00949 Tranylcypromine
|
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| Other DBs |
|
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| KCF data |
ATOM 25
1 C1y C 16.6589 -16.1557
2 C8y C 15.4841 -16.8746
3 C1y C 18.0323 -16.1557
4 C1x C 17.3486 -14.9167
5 C8x C 14.2976 -16.1557
6 C8x C 15.4841 -18.3007
7 N1a N 19.2247 -16.8746
8 C8x C 13.0994 -16.8746
9 C8x C 14.2976 -19.0197
10 C8x C 13.0994 -18.3007
11 S4a S 24.7388 -17.0375
12 O1d O 24.7330 -15.6405
13 O1d O 24.7330 -18.4343
14 O1d O 23.3420 -17.0316
15 O1d O 26.1356 -17.0375
16 C1y C 16.6589 -16.1557
17 C8y C 15.4841 -16.8746
18 C8x C 14.2976 -16.1557
19 C8x C 13.0994 -16.8746
20 C8x C 13.0994 -18.3007
21 C8x C 14.2976 -19.0197
22 C8x C 15.4841 -18.3007
23 C1y C 18.0323 -16.1557
24 N1a N 19.2247 -16.8746
25 C1x C 17.3486 -14.9167
BOND 26
1 11 12 2
2 11 13 2
3 11 14 1
4 11 15 1
5 1 2 1
6 1 3 1
7 1 4 1
8 2 5 2
9 2 6 1
10 3 7 1 #Up
11 5 8 1
12 6 9 2
13 8 10 2
14 3 4 1
15 9 10 1
16 16 17 1
17 16 23 1
18 16 25 1
19 17 18 2
20 17 22 1
21 23 24 1 #Up
22 18 19 1
23 22 21 2
24 19 20 2
25 23 25 1
26 21 20 1
BRACKET 1 12.6700 -19.6000 12.6700 -14.3500
1 21.0000 -14.3500 21.0000 -19.6000
1 2
ORIGINAL 1 1 2 5 8 10 9 6 3 7 4
REPEAT 1 16 17 18 19 20 21 22 23 24 25
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