KEGG   DRUG: D00826Help
Entry
D00826                      Drug                                   

Name
Tranylcypromine sulfate (USP XXI);
Parnate (TN)
Product
  Generic
Formula
(C9H11N)2. H2SO4
Exact mass
364.1457
Mol weight
364.4592
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Antidepressants
Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF04 Tranylcypromine
      D00826  Tranylcypromine sulfate (USP XXI)
USP drug classification [BR:br08302]
 Antidepressants
  Monoamine Oxidase Inhibitors
   Tranylcypromine
    D00826  Tranylcypromine sulfate (USP XXI)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO) [HSA:4128 4129] [KO:K00274]
    Tranylcypromine [ATC:N06AF04]
     D00826  Tranylcypromine sulfate
BRITE hierarchy
Other DBs
CAS: 
13492-01-8
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        25
            1   C1y C    16.6589  -16.1557
            2   C8y C    15.4841  -16.8746
            3   C1y C    18.0323  -16.1557
            4   C1x C    17.3486  -14.9167
            5   C8x C    14.2976  -16.1557
            6   C8x C    15.4841  -18.3007
            7   N1a N    19.2247  -16.8746
            8   C8x C    13.0994  -16.8746
            9   C8x C    14.2976  -19.0197
            10  C8x C    13.0994  -18.3007
            11  S4a S    24.7388  -17.0375
            12  O1d O    24.7330  -15.6405
            13  O1d O    24.7330  -18.4343
            14  O1d O    23.3420  -17.0316
            15  O1d O    26.1356  -17.0375
            16  C1y C    16.6589  -16.1557
            17  C8y C    15.4841  -16.8746
            18  C8x C    14.2976  -16.1557
            19  C8x C    13.0994  -16.8746
            20  C8x C    13.0994  -18.3007
            21  C8x C    14.2976  -19.0197
            22  C8x C    15.4841  -18.3007
            23  C1y C    18.0323  -16.1557
            24  N1a N    19.2247  -16.8746
            25  C1x C    17.3486  -14.9167
BOND        26
            1    11  12 2
            2    11  13 2
            3    11  14 1
            4    11  15 1
            5     1   2 1
            6     1   3 1
            7     1   4 1
            8     2   5 2
            9     2   6 1
            10    3   7 1 #Up
            11    5   8 1
            12    6   9 2
            13    8  10 2
            14    3   4 1
            15    9  10 1
            16   16  17 1
            17   16  23 1
            18   16  25 1
            19   17  18 2
            20   17  22 1
            21   23  24 1 #Up
            22   18  19 1
            23   22  21 2
            24   19  20 2
            25   23  25 1
            26   21  20 1
BRACKET     1    12.6700  -19.6000   12.6700  -14.3500
            1    21.0000  -14.3500   21.0000  -19.6000
            1  2
 ORIGINAL  1    1   2   5   8  10   9   6   3   7   4
 REPEAT    1   16  17  18  19  20  21  22  23  24  25

» Japanese version   » Back

DBGET integrated database retrieval system